The researches on total site process integration from the last decade of the 20th century until the present are reviewed. These researches include Total Site Profile，Top-level Analysis，and R-curve for optimal cogeneration and heat integration across plants. The strategy of comprehensive application of these technologies is described and the existing software packages are presented. The application cases and economic benefits worldwide are also summarized.

Research progress of the preparation of coal-based carbon molecular sieve (CMS) absorbents used for gas separation by pressure swing adsorption (PSA) is reviewed in this paper. Different preparation methods and their characteristics related to lignite，bituminous and anthracite coal as raw material are summarized. The effects of main preparation conditions on the structures and separation properties of coal-based CMSs are discussed in detail.

The functionally thermal fluids made by suspending fine phase change material (PCM) particles (dispersion phase) in a carrier fluid (continuum phase) have spontaneously flowability and large heat (or cold) storage. Some complex or nonlinear physical phenomena both in heat transfer and fluid flow are displayed. The natural convection characteristics of this kind of fluids are summarized，including heat transfer enhancement，stability，effects of particle size and some thermophysical properties. The future research on utilizing this kind of fluids was also discussed.

The state-of-the-art developments and progress of multi-scale mixing phenomena in micro-fluidics and nano-fluidics are reviewed. The approaches to characterizing multi-scale mixing phenomena are discussed. Some key issues and feasible methods for future research are also presented. Finally，several typical applications using micro-fluidics and nano-fluidics，including combined reaction，electrochemical reaction and DNA separation，are given.

Research results of flow patterns and phase inversion of oil-water two-phase flow in tubes are reviewed. The research advances in hydrodynamic characteristics of oil-water flow in a vertical pipe，such as drop size distribution，holdup，pressure drop，are particularly summarized. The existing problems in the research are analyzed and the research frontiers for further study on oil-water two-phase flow are also presented.

The separation of n-pentane，n-hexane and n-heptane mixture with the dividing wall column (DWC) was simulated with commercial software HYSYS，and the optimized operation region was obtained. The effects of feed property，such as feed thermal state，feed composition and relative volatility，on the operation of DWC were studied. The results demonstrated that the feed thermal state influenced strongly on the optimized operation region. And with the increase of the light component in the feed，the stable operation of DWC became more difficult. Furthermore，the simulation showed that relative volatility played an important role in energy saving and the operation of DWC. The more difficult the separation between the components，the better the effects of the separation. But the optimal operation region becomes narrow and unstable.

Differential evolution (DE) algorithm has many advantages，such as global optimum and high efficiency. A new predictive control algorithm based on DE was proposed，using DE to get the optimal control value. The algorithm had nothing to do with the type of the model，and it could be used in both linear and non-linear objects. The algorithm combined dynamic control and optimization in an index function，and used single-value predictive control. Application of the algorithm in CDU obtained good results，showing the feasibility and efficiency of the algorithm.

The conversion rate of dehydrogenation of ethylbenzene to styrene is important for the decision-making in the management of the chemical plant. In this paper，we applied a modified radial basis function (RBF) neural networks that could endure better fault-tolerace for this problem. The modified RBF neural networks was tested by six case history data sets，i.e.，the feed of the ethylbenzene，the temperatures of the first reactor and second reactor，the output pressure of the second reactor，the ratio of steam to ethylbenzene，the selectivity of the catalyst. The experiment showed that this method could ensure high accuracy in predicting the conversion rate of the process.

The energy-saving technology in balanced oxychlorination producing vinyl chloride monomer(VCM) was studied. Based on the mathematical simulation with ASPEN PLUS，the heat integration between distillation columns or columns and processes was adopted. By reducing the reflux ratio of VC1# distillation column and increasing the pressure of EDC2# distillation column，a higher temperature heat source was obtained. It could heat the reboilers of EDC1#，dehydration，EDC recovery distillation column. This scheme could save 178 740 t/y of steam，9 425 000 t/y of water and 25 660 000 yuan every year.

The rheological behavior of coal-oil slurry (COS) and coal-liquefied residue is fundamental information for direct coal liquefaction. The development and corresponding models of the rheological properties of Chinese COS under conditions，such as at ambient temperature under atmospheric pressure，during heating under normal pressure and at elevating temperature under high pressure，were summarized. The predominant factors affecting the viscosity of COS systems，such as the nature of solvent，the swelling property of coal，and the thermal dissolution or initial liquefied products were introduced. It could provide guidance for the research on rheology of COS and liquefaction residue.

Biomass gasification in the presence of steam was carried out to produce bio-gas in a fluidized bed reactor. The installation was made up of a fluidized bed reactor and a fixed bed cracking reactor. The feedstock was sawdust and the cracking catalyst included calcined dolomite and nickel-based reforming catalyst. The results showed that H2/CO (H/C) mole ratio greatly increased with increasing gasification temperature and steam/biomass mass ratio，but did not change much with increasing catalytic cracking temperature. In addition，in the catalytic cracking reactor using different kinds of catalysts would lead to different H/C. Two sections of catalytic cracking were used，sectionⅠwith calcined dolomite，and section Ⅱwith nickel-based catalyst. The tar cracking rate reached 96.70%. Using two sections of catalytic cracking not only would increase the tar cracking rate，increase the yield of H2 and CO，purify the biogas，but also could prevent the nickel-based reforming catalyst deactivation and extend its service life.