Abstract: The researches on total site process integration from the last decade of the 20th century until the present are reviewed. These researches include Total Site Profile，Top-level Analysis，and R-curve for optimal cogeneration and heat integration across plants. The strategy of comprehensive application of these technologies is described and the existing software packages are presented. The application cases and economic benefits worldwide are also summarized.

摘要： 对20世纪末至今全局过程集成技术的研究进展做了评述，从全局温焓曲线、顶层分析法、热电联产优化的R—曲线到跨装置热集成原理进行了比较系统地介绍。在此基础上，描述了综合使用这些基本方法的策略和现有的工具软件。最后将国外和国内在炼油和化工中应用全局过程集成技术的情况及经济效益分别做了归纳总结。