Abstract: Saccharide is not only an essential material base for maintaining normal life activities，but also an important biological information molecule．Fluorescent sensors，which are able to specifically recognize or label monosaccharides，has attracted much research interests．The recent progress of fluorescent monosaccharide sensors for glucose，N-acetylglucosamine，fructose，fucose，N-acetylmannosamine and N-acetylgalactosamine during the last several years is reviewed．The mechanism of fluorescence intensity change and the detection principle for each fluorescent monosaccharide sensor are introduced and the prospect of fluorescent monosaccharide sensors is presented．