关键词: 羧酸酯, 还原剂, 醇

Abstract: The reduction of carboxylic acid ester is an important reaction in organic chemistry and has extensive application in organic synthesis. The reduction systems used include borane，LiAlH4，diisobutyl aluminium hydride，sodium dihydro-bis-(2-methoxyethoxy)aluminate，and metal borohydrides reagent systems，wherein the reducing abilities of these systems are different. This paper introduces the progress of reduction systems mentioned above，and reviews reaction mechanism for each ester reaction. Comparison and examples of different reduction systems provide some ideas and methods for the study on reduction of carboxylic acid ester. The result of the reaction can be influenced by reactant ratio，addition sequence，and compatibility with different additives to achieve reaction yield up to 90% and moderate reaction. New agents，new methods with better selectivity，wider application，more moderate reaction conditions will contribute to new development of carboxylic ester reduction.

Key words: carboxylic acid esters, reductant, alcohols