Abstract: It is necessary to separate the amino acids from the fermentation broth during the process of amino acids production. The application of electro-membrane process(EMP) in the treatment of fermentation broth is becoming popular. This paper introduced the applications of conventional electrodialysis,bipolar membrane electrodialysis,ion-substitute electrodialysis and electrometathesis in fermentation industry,and described the stack configuration,the working principle and the application cases. It is also pointed out that the EMP can be used for the fractionation of amino acid mixtures,the desalination of fermentation broth and the production of amino acids from the corresponding salts. The process performance can be improved by optimizing stack configuration and operation parameters as well as applying novel membranes. It should be noted that the existing researches were mainly in experimental level and the simulated instead of real fermentation broth was used in the research,thus the reports of large-scale application were rarely available. However,it was predicted that the energy-efficient and environment-friendly electro-membrane process will play an important role in the treatment of amino acids fermentation broth in the future.

Key words: electro-membrane process, amino acids, fermentation broth, separation, desalination

摘要： 在发酵法生产氨基酸的过程中,需要后续工艺对发酵液进行分离纯化以提取目标产物.电驱动膜过程正逐渐成为该领域研究与应用的热点.本文介绍了近年来国内外普通电渗析(ED)、双极膜电渗析(BMED)、离子取代电渗析(ISED)、电复分解反应器(BMT)等常见的电驱动膜过程在氨基酸发酵液处理中的研究进展,简述了常见的膜堆构型及其工作原理、特点与应用实例.分析表明电驱动膜过程可以实现混合氨基酸分离、无机盐脱除以及氨基酸的制备,膜堆结构、操作参数的优化以及新型分离膜的研究与应用可以提高过程性能.同时也指出目前该领域的研究尚处于实验室研究阶段,研究对象以模拟发酵液为主,规模化应用的报道还不多见.但是可以预见高效、环保的电驱动膜过程将会在氨基酸发酵液处理中发挥重要作用.

关键词: 电驱动膜过程, 氨基酸, 发酵液, 分离, 脱盐