辣素衍生物改性PVDF膜的制备及其抗菌性能

doi:10.16085/j.issn.1000-6613.2019-0378

摘要/Abstract

摘要：

以甲基丙烯酸甲酯（MMA）和天然辣素8-甲基-N-香草基-6-壬烯酰胺（Capsa）为单体，通过自由基聚合合成辣素衍生物PMMA-Capsa。将PMMA-Capsa与聚偏氟乙烯（PVDF）共混，通过非溶剂诱导相转化法制备PVDF/PMMA-Capsa分离膜，系统地研究了PMMA-Capsa含量对所制备的分离膜表面化学组成、形态结构、亲水性能、抗菌性能及渗透性能的影响。结果表明在成膜过程中PMMA-Capsa倾向于分布在分离膜的表面和孔道表面。随着铸膜液中PMMA-Capsa含量的增加，所制备的分离膜断面结构中海绵层结构逐渐消失，分离膜容易形成粗糙的微孔状表面。PMMA-Capsa的引入使分离膜表面水接触角从88.4°降低到73.1°。渗透实验结果表明分离膜的纯水通量随着PMMA-Capsa含量的增加而增加，而对牛血清蛋白（BSA）的截留率逐渐降低，所制备的PVDF/PMMA-Capsa分离膜的通量恢复率高于纯PVDF膜。PVDF/PMMA-Capsa分离膜具有优异的抗菌性能，对金黄色葡萄球菌的抗菌效率最高可达97.2%。

关键词: 聚合物, 膜, 界面, 混合, 分离, 聚偏氟乙烯, 抗菌活性, 辣素

Abstract:

Capsaicin derivative(PMMA-Capsa) was synthesized via radical copolymerization using methyl methacrylate(MMA) and 8-methyl-N-vanillyl-6-nonenamide (Capsa) as monomers. PMMA-Capsa was blended with PVDF to prepare the PVDF/PMMA-Capsa membrane using non-solvent induced phase inversion method. Effects of PMMA-Capsa concentration on the surface chemical composition, morphology, hydrophilicity, anti-bacterial activities and permeation properties of resultant membranes were investigated systematically. The result showed that the PMMA-Capsa was inclined to distribute onto the membrane surface and pore channel surface during the membrane formation process. With the increase of PMMA-Capsa concentration in the casting solution, the sponge-like structure at the cross-sections of membranes disappeared gradually, and the microporous and rough membrane surfaces were easily formed. The introduction of PMMA-Capsa resulted in the decrease in water contact angle of membrane surface from 88.4° to 73.1°. Filtration experiments indicated that the pure water flux of the membranes increased, whereas the rejection ratio of bovine serum albumin(BSA) decreased with the increment of PMMA-Capsa concentration. The flux recovery ratios of the prepared PVDF/PMMA-Capsa membranes were higher than that of the pristine PVDF membrane. The PVDF/PMMA-Capsa membrane exhibited excellent biofouling resistance and the bactericidal efficiency against S. aureu was as high as 97.2%.

Key words: polymers, membrane, interface, blend, separation, poly(vinylidene fluoride), anti-bacterial activity, capsaicin

中图分类号:

TQ322.2

申向,刘开全,刘鹏,姚思杰,吕妮娜,张永金,汪帆. 辣素衍生物改性PVDF膜的制备及其抗菌性能[J]. 化工进展, 2019, 38(12): 5427-5434.

Xiang SHEN,Kaiquan LIU,Peng LIU,Sijie YAO,Nina LÜ,Yongjin ZHANG,Fan WANG. Preparation and anti-bacterial ability of PVDF membrane modifiedwith capsaicin derivative[J]. Chemical Industry and Engineering Progress, 2019, 38(12): 5427-5434.

图/表 12

参考文献 20

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膜样品	PMMA-Capsa/g	NMP/g
M0	0.00	30.50
M1	0.06	30.44
M2	0.18	30.32
M3	0.30	30.20

膜样品	PMMA-Capsa/g	NMP/g
M0	0.00	30.50
M1	0.06	30.44
M2	0.18	30.32
M3	0.30	30.20

样品	C1s	F1s	O1s	N1s	CF₂	CO	CH	CN/COH/COC/CH₂	(CO/CF₂)_t	(CO/CF₂)_e
M0	52.66	44.52	2.82	—	44.01	—	4.27	51.72	—	—
M1	50.40	39.10	9.22	1.28	32.81	4.31	8.55	54.33	0.006	0.131
M2	59.66	24.37	13.77	2.20	15.61	9.34	24.61	50.44	0.018	0.598
M3	61.84	10.89	23.50	3.78	6.20	14.62	33.50	45.68	0.030	2.358

样品	C1s	F1s	O1s	N1s	CF₂	CO	CH	CN/COH/COC/CH₂	(CO/CF₂)_t	(CO/CF₂)_e
M0	52.66	44.52	2.82	—	44.01	—	4.27	51.72	—	—
M1	50.40	39.10	9.22	1.28	32.81	4.31	8.55	54.33	0.006	0.131
M2	59.66	24.37	13.77	2.20	15.61	9.34	24.61	50.44	0.018	0.598
M3	61.84	10.89	23.50	3.78	6.20	14.62	33.50	45.68	0.030	2.358

膜样品	R_a/nm	r_m/nm	ε/%
M0	16.3	82.7	68.6
M1	18.1	103.7	71.1
M2	21.5	146.1	74.1
M3	22.7	152.9	75.7