关键词: C16, C18, 混合脂肪酸, 分离, 精馏, 结晶, 碳16, 碳18, 混合脂肪酸, 分离, 精馏, 结晶

Abstract: C16 and C18 fatty acid mixtures contain many high value components. Separating these components could greatly increase profit. So it is of great importance to study the separation technology of C16 and C18 fatty acid mixtures. Development of C16 and C18 fatty acid mixtures separation technology in the recent 10 years is reviewed，such as vacuum distillation，urea inclusion，π-complexing with Ag+，low temperature crystallization，and lipase-catalyzed method. The advantages and disadvantages of such separation methods are discussed. Vacuum distillation can effectively separate fatty acid mixtures into C16 and C18 components. Its main problem is that unsaturated components are prone to isomerization and polymerization under heating. Urea inclusion is usually used to separate saturated and unsaturated components in C16 and C18 mixtures. Current research on this method is focused on optimization and improvement of operating conditions. Lipase-catalyzed method is of high selectivity，environmentally friendly and can be operated under mild conditions. Now it has been used to concentrate α-linolenic acid and γ-linolenic acid，achieving good separation results. The prospects of C16 and C18 fatty acid mixtures separation technology are analyzed，pointing out that combination of two or more methods and lipase-catalyzed method will be the future tendency.

Key words: C16, C18, fatty acid mixtures, separation, distillation, crystallization, C16, C18, fatty acid mixtures, separation, distillation, crystallization