具有pH响应性的自愈合蓝光水凝胶

doi:10.16085/j.issn.1000-6613.2022-1944

化工进展 ›› 2023, Vol. 42 ›› Issue (9): 4837-4846.DOI: 10.16085/j.issn.1000-6613.2022-1944

具有pH响应性的自愈合蓝光水凝胶

王少凡¹(), 周颖¹, 郝康安², 黄安荣³, 张如菊¹, 吴翀⁴(), 左晓玲¹()

^1.贵州民族大学材料科学与工程学院，贵州贵阳 550025
^2.贵州民族大学机械与电子工程学院，贵州贵阳 550025
^3.国家复合改性聚合物材料工程技术研究中心，贵州贵阳 550014
^4.贵州中医药大学药学院，贵州贵阳 550025

收稿日期:2022-10-19 修回日期:2022-12-19 出版日期:2023-09-15 发布日期:2023-09-28
通讯作者: 吴翀,左晓玲
作者简介:王少凡（1997—），硕士研究生，研究方向为智能材料的研发与制备。E-mail：18627816569@163.com
基金资助:
国家自然科学基金(81903799);贵州省科学技术基金(ZK[2022]029)

Self-healing and blue-light hydrogel with pH responsiveness

WANG Shaofan¹(), ZHOU Ying¹, HAO Kang’an², HUANG Anrong³, ZHANG Ruju¹, WU Chong⁴(), ZUO Xiaoling¹()

^1.College of Materials Science and Engineering, Guizhou Minzu University, Guiyang 550025, Guizhou, China
^2.College of Mechanical and Electrical Engineering, Guizhou Minzu University, Guiyang 550025, Guizhou, China
^3.National Engineering Research Center for Compounding and Modification of Polymeric Materials, Guiyang 550014, Guizhou, China
^4.College of Pharmacy, Guizhou University of Traditional Chinese Medicine, Guiyang 550025, Guizhou, China

Received:2022-10-19 Revised:2022-12-19 Online:2023-09-15 Published:2023-09-28
Contact: WU Chong, ZUO Xiaoling

摘要/Abstract

摘要：

通过分子设计，以改性壳聚糖与改性海藻酸钠通过席夫碱键交联，制备了一种低成本且具有多功能集成特性的新型荧光自愈合水凝胶（CSA水凝胶）。研究分析结果表明，该水凝胶表现出快速的凝胶化能力，最短仅在3min内即可成胶。并且水凝胶还表现出优异的自愈合能力，在室温下最快2h即可实现自主型自愈合，且愈合效率高。同时，在365nm紫外光的照射下，CSA水凝胶能够稳定释放出强烈的蓝色荧光，同时表现出荧光激发波长依赖特性。此外，调节水凝胶的pH能够很好地实现水凝胶的溶胶-凝胶相转变，进而实现凝胶的动态重组。这种同时具备pH响应性、自愈合特性以及荧光性能的水凝胶材料，为开发可用于生物影像和信息防伪领域的新一代智能材料提供了新的思路和重要指导作用。

关键词: 水凝胶, 自愈合, 荧光, pH响应, 壳聚糖, 海藻酸钠

Abstract:

Based on the molecular design, a novel fluorescent self-healing hydrogel (CSA Hydrogel) with low cost and multi-functional integration properties was synthesized by the modified chitosan and sodium alginate via Schiff base crosslinking. The result was found that the hydrogel had a rapid gelatinization ability and the shortest time was 3 minutes. The hydrogel also showed the excellent self-healing ability, concretely, the self-healing phenomenon could be realized with the shortest time of 2 hours at room temperature and the self-healing efficiency was high. It was worth noting that CSA hydrogels can stably release strong blue fluorescence under 365nm UV light, and show the wavelength dependence of fluorescence excitation. In addition, the sol-gel phase transition of hydrogels could be realized by adjusting the pH of hydrogels, and then the dynamic recombination of hydrogels could be achieved. The hydrogel materials with pH responsiveness, self-healing properties and fluorescence properties provided a new idea and an important guidance for the development of a new generation of smart materials, which could be used in the field of biological imaging and information security.

Key words: hydrogel, self-healing, fluorescence, pH response, chitosan, sodium alginate

中图分类号:

O636.9

王少凡, 周颖, 郝康安, 黄安荣, 张如菊, 吴翀, 左晓玲. 具有pH响应性的自愈合蓝光水凝胶[J]. 化工进展, 2023, 42(9): 4837-4846.

WANG Shaofan, ZHOU Ying, HAO Kang’an, HUANG Anrong, ZHANG Ruju, WU Chong, ZUO Xiaoling. Self-healing and blue-light hydrogel with pH responsiveness[J]. Chemical Industry and Engineering Progress, 2023, 42(9): 4837-4846.

图/表 7

参考文献 37

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代号	去离子水 /mL	NA-CMCs /g	OSA /g	凝胶化时间 /min	状态
CSA-10	4	0.2	0.225	3	固态，硬
CSA-9	4	0.18	0.2025	10	固态，硬
CSA-8	4	0.16	0.18	14	固态，略硬
CSA-7	4	0.14	0.1575	30	固态，略硬
CSA-6	4	0.12	0.135	50	固态，略软
CSA-5	4	0.1	0.1125	253	固态，略软
CSA-4	4	0.08	0.09	600	固态，软
CSA-3	4	0.06	0.0675	—	微凝胶态
CSA-2	4	0.04	0.045	—	液态
CSA-1	4	0.02	0.0225	—	液态

代号	去离子水 /mL	NA-CMCs /g	OSA /g	凝胶化时间 /min	状态
CSA-10	4	0.2	0.225	3	固态，硬
CSA-9	4	0.18	0.2025	10	固态，硬
CSA-8	4	0.16	0.18	14	固态，略硬
CSA-7	4	0.14	0.1575	30	固态，略硬
CSA-6	4	0.12	0.135	50	固态，略软
CSA-5	4	0.1	0.1125	253	固态，略软
CSA-4	4	0.08	0.09	600	固态，软
CSA-3	4	0.06	0.0675	—	微凝胶态
CSA-2	4	0.04	0.045	—	液态
CSA-1	4	0.02	0.0225	—	液态

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具有pH响应性的自愈合蓝光水凝胶

Self-healing and blue-light hydrogel with pH responsiveness

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