HMF路线合成生物基单体2,5-呋喃二甲酸的研究进展

doi:10.16085/j.issn.1000-6613.2017-1856

摘要/Abstract

摘要： 2，5-呋喃二甲酸（FDCA）是合成聚（呋喃二甲酸乙二醇酯）（PEF）等生物基聚酯的重要单体，具有广阔的应用前景。FDCA能否实现低廉、高效的大规模生产，是生物基聚酯开发的关键。目前，FDCA合成的研究广受关注，工业化开发也正在进行中。本文对合成生物基单体FDCA的5-羟甲基糠醛（HMF）路线进行综述，重点介绍了水、高沸点有机溶剂、低沸点有机溶剂、双相体系和离子液体中的糖类脱水合成HMF，无碱水溶液、碱性水溶液和有机溶剂中的HMF氧化合成FDCA以及糖类一锅法合成FDCA的研究进展。在比较各种合成方法的基础上，认为当前应着重研究开发低沸点溶剂中糖类脱水合成HMF以及无碱水溶液或有机溶剂中低廉高效的HMF氧化新方法，并向着糖类一锅法合成FDCA的方向发展。

关键词: 2, 5-呋喃二甲酸, 5-羟甲基糠醛, 生物基单体, 生物基聚酯, 糖类

Abstract: 2,5-Furandicarboxylic acid (FDCA) is an important bio-based monomer with broad market prospect in producing the bio-based polyesters, such as poly(ethylene furandicarboxylate) (PEF). Production of FDCA in large scale with high efficiency and low cost is the key for development of FDCA-based polyesters. At present, R&D of FDCA has attracted extensive attention from academy to industry. In this paper, the 5-hydroxymethylfurfural (HMF) route for FDCA synthesis was reviewed, including HMF synthesis via dehydration of sugar in water, high boiling point organic solvent, low boiling point organic solvent, two-phase solvent system and ionic liquid, FDCA synthesis via oxidation of HMF in base-free water, base solution and organic solvent, and one-pot FDCA synthesis from sugar. Based on comparison of various reported methods, perspectives are given that the FDCA R&D should be focus on the sugar dehydration to HMF in low boiling point solvent and HMF oxidation to FDCA in base-free water or organic solvent, which will establish the foundation for eventually realizing inexpensive and efficient one-pot FDCA synthesis directly from sugar without separation of the intermediate HMF.

Key words: 2,5-furandicarboxylic acid, 5-hydroxymethylfurfural, bio-based monomer, bio-based polyester, sugar

中图分类号:

O643.3

陈光宇, 吴林波, 李伯耿. HMF路线合成生物基单体2,5-呋喃二甲酸的研究进展[J]. 化工进展, 2018, 37(08): 3146-3154.

CHEN Guangyu, WU Linbo, LI Bogeng. Progress in the synthesis of bio-based monomer 2,5-furandicarboxylic acid through 5-hydroxymethylfurfural route[J]. Chemical Industry and Engineering Progress, 2018, 37(08): 3146-3154.

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