Abstract: The electrophoretic membrane contactor (EMC) is a novel membrane separation technology in which porous membranes are stacked or replaced partial ion exchange membranes by porous membranes in conventional electrodialysis cell. The porous membranes act as the contact interface between the two liquid streams where the mass transfer takes place. The voltage，applied in a direction perpendicular to the flows，is the only driving force. This review paper described the principles of EMC. Cell configuration and operation mode of EMC were briefly discussed. The influences of important operation factors，such as pH of solution and electric field strength，polymer materials and molecular weight cutoff of porous membranes on the mass transfer of EMC process were analyzed in detail. Pollution status of the porous membranes during the operation of EMC was explored and the application potential of EMC in separation and purification of biomacromolecules was discussed. EMC further extends the application field of electrodialysis by using of porous membrane，which could be used in separation and purification of biomolecules greater than 500 Da. Membrane fouling could be effectively minimized due to external electric field.

Key words: electrophoretic membrane contactor, electrodialysis, ultra?ltration membranes

摘要： 电泳膜接触器（EMC）是在传统电渗析器中引入多孔膜，或用多孔膜代替部分离子交换膜的一种新型膜分离技术，其中多孔膜作为两液流的接触界面，提供传质的场所，垂直于液流方向的电场是唯一的驱动力。本文介绍了EMC的工作原理，并简要概述了EMC的膜堆构型及运行模式。详细分析了进料液pH值、电场强度等操作参数、多孔膜的材质和截留相对分子质量等对EMC过程传质的影响，且对EMC运行过程中多孔膜的污染状况进行了探讨，并展望了EMC在生物大分子分离和纯化中的应用潜力。EMC中多孔膜的引入，使得EMC可以用于相对分子质量大于500 Da的生物分子的分离与纯化，进一步拓宽了电渗析的应用领域，而外加电场的作用能够有效减轻多孔膜的污染，因此，EMC在生物分子的分离与纯化方面具有广阔的应用前景。

关键词: 电泳膜接触器, 电渗析, 超滤膜