关键词: 白藜芦醇, 衍生物, 类似物, 抗肿瘤活性, 作用机制

Abstract: Resveratrol has extensive biological activities，especially its anti-tumor effect，so its pharmacological properties have been studied. At the same time，in order to improve the bioavailability，and obtain a higher antitumor activity，studies on their derivatives and analogues have been widely carried out. In this paper，the items of chemical structure，physical and chemical properties，antitumor mechanism，genetic toxicity，kinetics of resveratrol and the antitumor activity and mechanism of resveratrol derivatives and analogues were reviewed. There are still many needs to continue to study in this area. Its biological mechanism of action，relationship between structure and activity，bioavailability and efficacy，and pharmacokinetics studies need to be further investigated. As a new promising anticancer drug，a systematic study on its effect mechanism，toxicology，pharmacokinetics，animal experiment of resveratrol，its derivatives and analogues need to be carried out.

Key words: resveratrol, derivatives, analogues, anti-tumor activity, mechanism