化工进展

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磁辅助生物反应器研究进展

林檬,陈国,赵珺   

  1. 华侨大学化工学院生物工程与生物技术系,福建 厦门 361021
  • 出版日期:2014-05-05 发布日期:2014-05-05

Research progress of magnetically assisted bioreactor

LIN Meng,CHEN Guo,ZHAO Jun   

  1. Department of Biological Engineering and Biological Technology,School of Chemical Engineering,Huaqiao University,Xiamen 361021,Fujian,China
  • Online:2014-05-05 Published:2014-05-05

摘要: 磁辅助生物反应器通过辅助磁场直接控制磁性生物载体的运动,有效改善传质及颗粒间的相对运动,兼具固定床、悬浮床、移动床及流化床反应器的优点,具有广阔的应用前景。本文首先从磁性材料、载体材料及构建方法的角度介绍了各类磁性生物载体的特征;总结了轴向电磁场、径向电磁场、永磁体磁场的构建原理及方法;对磁辅助搅拌罐反应器、磁辅助固定床反应器、磁辅助流化床反应器、磁稳流化床反应器的结构特点及其在生化过程中的应用进行了阐述。最后指出磁辅助生物反应器的研究仍停留在实验室水平,其发展有赖于良好生物亲和性的磁生物载体的开发、可控均一辅助磁场的放大及反应器的优化设计。

关键词: 生物反应器, 固定化, 生物载体, 磁场, 流化床, 生物反应器, 固定化, 生物载体, 磁场, 流化床

Abstract: Magnetically assisted bioreactors directly control the motion of magnetic bio-supports by assisting magnetic field,which improves mass transfer and relative motion between catalyst particles and can be combined with the advantages of fixed-bed,slurry-bed,moving-bed and fluidized-bed reactors. In this paper,magnetic bio-supports are characterized from three aspects,including magnetic material,carrier material and construction method;basic principles for construction of axial/transverse electromagnetic field and permanent magnetic field are summarized;configurations of magnetically assisted stirred reactor,magnetically assisted fixed-bed,magnetically assisted fluidized-bed and magnetically stabilized fluidized-bed reactor as well as their applications in biological and chemical processing are presented. Finally,research of magnetically assisted bioreactor is still in the laboratory,and further development asks for novel bio-compatible magnetic supports,controllable homogeneous large-scale assisted magnetic field and more creative reactor design.

Key words: bioreactors, immobilization, biosupport, magnetic field, fluidized-bed, bioreactors, immobilization, bio-support, magnetic field, fluidized-bed

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