关键词: N-马来酰化壳聚糖, 反应, 配合物, 合成, 表征

Abstract: The decrystal chitosan was achieved by treating the chitosan raw material in alkaline solution. Its structure was confirmed by the Fourier transform infrared spectra (FT-IR). The N-maleoyl chitosan (CTM) was synthesized in N,N-dimethyl formamide (DMF) and anhydrous ethanol (EtOH) solution through acylation reaction between the maleic anhydride and decrystal chitosan by the mole ratio of 1∶1 for 18 hours at room temperature. The substitution degree of obtained N-maleoyl chitosan was 63%. The FT-IR spectrum shows that the maleic anhydride is successfully grafted onto the —NH2 of chitosan. The N-maleoyl chitosan further reacted with copper chloride and zinc chloride for 6 hours at room temperature to provide the metal complexes CTMCu and CTMZn，respectively. The structures of N-maleoyl chitosan and its complexes were investigated by FT-IR and electron paramagnetic resonance (EPR) spectra. The results show that the N-maleoyl chitosan can react with Cu(Ⅱ) and Zn(Ⅱ) ions in mild condition. And the carboxylate and amino groups chelate the metal center.

Key words: N-maleoyl chitosan, reaction, complexes, synthesis, characterization