微流控模板法制备功能化非球形微颗粒研究新进展

doi:10.16085/j.issn.1000-6613.2018-2226

摘要/Abstract

摘要：

功能化非球形微颗粒在生物医药、吸附、传感与检测等方面具有非常广泛的应用。相对于其他非球形微颗粒制备方法，近年来兴起的微流控技术，由于对微尺度流体具有超灵敏的操控特性，在制备和精确调控微米级功能材料方面具有很大的优势。通过精确控制流体在微尺度通道内的流动和剪切，微流控技术可以实现多种形态和结构的微尺度流体、乳液和纤维的可控构建，为非球形微颗粒的可控制造提供了优良的模板。同时，通过在制备过程中引入功能性材料，这些非球形微颗粒将具备更多的功能，从而极大地拓展和丰富了其应用范围。本文综述了近年来采用微流控技术制备功能化非球形微颗粒的研究新进展，重点介绍了以微流控技术构建得到的微流体、多相乳液及微纤维为模板可控制备功能化非球形微颗粒的研究现状。

关键词: 微流控, 模板, 非球形, 微颗粒

Abstract:

Functional non-spherical microparticles are widely used in myriad applications, such as biomedicine, adsorption, sensing and detecting. Compared with other methods for preparing non-spherical microparticles, microfluidic technique has great advantages in the fabrication and regulation of micron-sized functional materials due to its excellent manipulation of microflows. By precisely controlling the flow and shear of fluids in microscale channels, microfluidic technology enables the controllable construction of microflows, microemulsions and microfibers of various morphologies and structures, which provides excellent templates for manufacturing non-spherical microparticles. Moreover, these non-spherical microparticles can be endowed with more functionalities by introducing functional materials, which greatly expands and enriches their applications. This review summarizes recent progress of microfluidic fabrication of functional non-spherical microparticles. Emphases are focused on controllable fabrication of functional non-spherical microparticles by using microflows, microemulsions and microfibers as templates.

Key words: microfluidics, templates, non-spherical, microparticles

中图分类号:

O631

何晓恒,褚良银. 微流控模板法制备功能化非球形微颗粒研究新进展[J]. 化工进展, 2019, 38(9): 4109-4118.

Xiaoheng HE,Liangyin CHU. Recent progress of fabrication of functional non-spherical microparticles from microfluidic templates[J]. Chemical Industry and Engineering Progress, 2019, 38(9): 4109-4118.

图/表 2

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