茶树油/脲醛树脂缓释微胶囊的制备

doi:10.16085/j.issn.1000-6613.2017.05.039

化工进展 ›› 2017, Vol. 36 ›› Issue (05): 1862-1867.DOI: 10.16085/j.issn.1000-6613.2017.05.039

茶树油/脲醛树脂缓释微胶囊的制备

龚圣¹, 陈燕¹, 韩文强¹, 周新华¹, 徐华¹, 陈铧耀¹, 吴伟超²

1. 仲恺农业工程学院化学化工学院, 广东广州 510225;
2. 河源市润天然生物科技有限公司, 广东河源 517000

收稿日期:2016-08-05 修回日期:2017-01-04 出版日期:2017-05-05 发布日期:2017-05-05
通讯作者: 周新华,博士,教授,主要从事农业精细化学品研究。
作者简介:龚圣(1978-),男,博士,副教授,硕士生导师,主要从事农业精细化学品研究。E-mail:gshengjx@163.com。
基金资助:
国家留学基金委项目（201508440427）、广东省科技计划（2016A010103036，2015A020209182）以及广州市科技计划项目（201510010964）

Preparation of tea tree oil/urea formaldehyde-resin sustained release microcapsules

GONG Sheng¹, CHEN Yan¹, HAN Wenqiang¹, ZHOU Xinhua¹, XU Hua¹, CHEN Huayao¹, WU Weichao²

1. College of Chemistry and Chemical Engineering, Zhongkai University of Agriculture and Engineering, Guangzhou 510225, Guangdong, China;
2. Heyuan Runtianran Bio-tech Co., Ltd., Heyuan 517000, Guangdong, China

Received:2016-08-05 Revised:2017-01-04 Online:2017-05-05 Published:2017-05-05

摘要/Abstract

摘要： 以甲醛和尿素为微胶囊壁材原料，以茶树精油为芯材，采用原位聚合法制备茶树油/脲醛树脂微胶囊，能够弥补茶树油易挥发、易氧化和气味难闻的缺点。本文考察乳化剂的种类、乳化剂的用量、释放环境等因素对微胶囊的形貌、粒径、载药量以及缓释性能的影响。研究结果表明，以十二烷基硫酸钠为乳化剂，用量约为4%，固化时间为80min时，所得的载油微胶囊形状规则、外表圆滑、粒径均匀、平均约40~50μm，囊壁致密、壁厚约0.5μm。此外，载药量和缓释性能较好，本文研究制得的微胶囊载药量可达45%左右，4天释放量为68%左右，室温条件下微胶囊释放时长可达7天。

关键词: 茶树油, 脲醛树脂, 微胶囊, 粒径, 缓释

Abstract: Using formaldehyde and urea as wall material of microcapsule and tea tree oil as core material,tea tree oil/urea formaldehyde resin microcapsules were prepared by in-situ polymerization so the adverse influence of volatile,oxidation and unpleasant smell could be avoided reasonably. In this study,the effects of the types of emulsifier,the amount of emulsifier,the curing time,the release of the environment, and other factors on the morphology,particle size,drug loading,and release properties of microcapsules were investigated. The results showed that,with the amount of 4% twelve sodium alkyl sulfate as emulsifier,the curing time about 80min,a good-shaped tea tree oil/urea formaldehyde resin microcapsule had been prepared with the most normal appearance,and uniform particle size,about 40-50μm,and compact wall. Furthermore,the tea tree oil loading and release performance was better. In this study,the microcapsule drug loading was up to about 45%,and 4 days release amount was about 68% under room temperature. Moreover,the duration of microcapsule release could be up to 7 days.

Key words: tea tree oil, urea-formaldehyde resin, microcapsule, particle size, sustained release

中图分类号:

TQ658

龚圣, 陈燕, 韩文强, 周新华, 徐华, 陈铧耀, 吴伟超. 茶树油/脲醛树脂缓释微胶囊的制备[J]. 化工进展, 2017, 36(05): 1862-1867.

GONG Sheng, CHEN Yan, HAN Wenqiang, ZHOU Xinhua, XU Hua, CHEN Huayao, WU Weichao. Preparation of tea tree oil/urea formaldehyde-resin sustained release microcapsules[J]. Chemical Industry and Engineering Progress, 2017, 36(05): 1862-1867.

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茶树油/脲醛树脂缓释微胶囊的制备

Preparation of tea tree oil/urea formaldehyde-resin sustained release microcapsules

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