Chemical Industry and Engineering Progress ›› 2023, Vol. 42 ›› Issue (S1): 400-410.DOI: 10.16085/j.issn.1000-6613.2023-0424
• Fine chemicals • Previous Articles Next Articles
Received:
2023-03-21
Revised:
2023-07-09
Online:
2023-11-30
Published:
2023-10-25
Contact:
LI Sifang
通讯作者:
黎四芳
作者简介:
王正坤(1993—),男,硕士研究生,研究方向为精细化工。E-mail:zkwang@stu.xmu.edu.cn。
CLC Number:
WANG Zhengkun, LI Sifang. Green synthesis of gemini surfactant decyne diol[J]. Chemical Industry and Engineering Progress, 2023, 42(S1): 400-410.
王正坤, 黎四芳. 双子表面活性剂癸炔二醇的绿色合成[J]. 化工进展, 2023, 42(S1): 400-410.
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URL: https://hgjz.cip.com.cn/EN/10.16085/j.issn.1000-6613.2023-0424
实验因素 | 水平 | ||
---|---|---|---|
-1 | 0 | 1 | |
反应温度(A)/℃ | 25 | 35 | 45 |
反应时间(B)/h | 6 | 9 | 12 |
异丁醇钾与甲基异丁基酮摩尔比(C) | 1∶1 | 1.5∶1 | 2∶1 |
溶剂用量(D) | 3∶1 | 4.5∶1 | 6∶1 |
实验因素 | 水平 | ||
---|---|---|---|
-1 | 0 | 1 | |
反应温度(A)/℃ | 25 | 35 | 45 |
反应时间(B)/h | 6 | 9 | 12 |
异丁醇钾与甲基异丁基酮摩尔比(C) | 1∶1 | 1.5∶1 | 2∶1 |
溶剂用量(D) | 3∶1 | 4.5∶1 | 6∶1 |
序号 | 实验因素 | S104收率/% | |||
---|---|---|---|---|---|
A/℃ | B/h | C | D | ||
1 | 25 | 9 | 1 | 4.5 | 56.78 |
2 | 35 | 12 | 1 | 4.5 | 70.95 |
3 | 35 | 12 | 2 | 4.5 | 86.01 |
4 | 35 | 6 | 1.5 | 3 | 75.86 |
5 | 35 | 9 | 1.5 | 4.5 | 87.48 |
6 | 45 | 9 | 2 | 4.5 | 80.87 |
7 | 45 | 6 | 1.5 | 4.5 | 76.77 |
8 | 35 | 9 | 1.5 | 4.5 | 84.61 |
9 | 35 | 12 | 1.5 | 6 | 86.42 |
10 | 35 | 6 | 1.5 | 6 | 75.09 |
11 | 35 | 9 | 2 | 3 | 85.88 |
12 | 25 | 9 | 1.5 | 6 | 71.58 |
13 | 25 | 9 | 2 | 4.5 | 76.97 |
14 | 35 | 6 | 2 | 4.5 | 83.86 |
15 | 35 | 9 | 1.5 | 4.5 | 86.41 |
16 | 35 | 9 | 1.5 | 4.5 | 84.89 |
17 | 35 | 9 | 1 | 3 | 68.77 |
18 | 45 | 9 | 1.5 | 6 | 83.54 |
19 | 25 | 9 | 1.5 | 3 | 69.03 |
20 | 35 | 9 | 1.5 | 4.5 | 86.59 |
21 | 35 | 9 | 2 | 6 | 88.23 |
22 | 25 | 6 | 1.5 | 4.5 | 69.02 |
23 | 35 | 9 | 1 | 6 | 69.23 |
24 | 35 | 12 | 1.5 | 3 | 83.4 |
25 | 45 | 9 | 1.5 | 3 | 80.98 |
26 | 45 | 9 | 1 | 4.5 | 68.96 |
27 | 35 | 6 | 1 | 4.5 | 62.98 |
28 | 45 | 12 | 1.5 | 4.5 | 83.87 |
29 | 25 | 12 | 1.5 | 4.5 | 74.32 |
序号 | 实验因素 | S104收率/% | |||
---|---|---|---|---|---|
A/℃ | B/h | C | D | ||
1 | 25 | 9 | 1 | 4.5 | 56.78 |
2 | 35 | 12 | 1 | 4.5 | 70.95 |
3 | 35 | 12 | 2 | 4.5 | 86.01 |
4 | 35 | 6 | 1.5 | 3 | 75.86 |
5 | 35 | 9 | 1.5 | 4.5 | 87.48 |
6 | 45 | 9 | 2 | 4.5 | 80.87 |
7 | 45 | 6 | 1.5 | 4.5 | 76.77 |
8 | 35 | 9 | 1.5 | 4.5 | 84.61 |
9 | 35 | 12 | 1.5 | 6 | 86.42 |
10 | 35 | 6 | 1.5 | 6 | 75.09 |
11 | 35 | 9 | 2 | 3 | 85.88 |
12 | 25 | 9 | 1.5 | 6 | 71.58 |
13 | 25 | 9 | 2 | 4.5 | 76.97 |
14 | 35 | 6 | 2 | 4.5 | 83.86 |
15 | 35 | 9 | 1.5 | 4.5 | 86.41 |
16 | 35 | 9 | 1.5 | 4.5 | 84.89 |
17 | 35 | 9 | 1 | 3 | 68.77 |
18 | 45 | 9 | 1.5 | 6 | 83.54 |
19 | 25 | 9 | 1.5 | 3 | 69.03 |
20 | 35 | 9 | 1.5 | 4.5 | 86.59 |
21 | 35 | 9 | 2 | 6 | 88.23 |
22 | 25 | 6 | 1.5 | 4.5 | 69.02 |
23 | 35 | 9 | 1 | 6 | 69.23 |
24 | 35 | 12 | 1.5 | 3 | 83.4 |
25 | 45 | 9 | 1.5 | 3 | 80.98 |
26 | 45 | 9 | 1 | 4.5 | 68.96 |
27 | 35 | 6 | 1 | 4.5 | 62.98 |
28 | 45 | 12 | 1.5 | 4.5 | 83.87 |
29 | 25 | 12 | 1.5 | 4.5 | 74.32 |
方差来源 | 平方和 | 自由度 | 均方 | F | P | 显著性 |
---|---|---|---|---|---|---|
回归方程 | 1936.259 | 14 | 138.3042 | 51.60691 | < 0.0001 | + + |
反应温度A | 273.512 | 1 | 273.512 | 102.0584 | < 0.0001 | + + |
反应时间B | 142.761 | 1 | 142.761 | 53.26993 | < 0.0001 | + + |
异丁醇钾与甲基异丁基酮摩尔比C | 903.9352 | 1 | 903.9352 | 337.2949 | < 0.0001 | + + |
溶剂用量D | 8.619075 | 1 | 8.619075 | 3.216127 | 0.0945 | |
AB | 0.81 | 1 | 0.81 | 0.302244 | 0.5911 | |
AC | 17.1396 | 1 | 17.1396 | 6.395481 | 0.0241 | + |
AD | 2.5×10-5 | 1 | 2.5×10-5 | 9.33×10-6 | 0.9976 | |
BC | 8.4681 | 1 | 8.4681 | 3.159792 | 0.0972 | |
BD | 3.591025 | 1 | 3.591025 | 1.339957 | 0.2664 | |
CD | 0.893025 | 1 | 0.893025 | 0.333224 | 0.5729 | |
A2 | 378.1677 | 1 | 378.1677 | 141.1097 | < 0.0001 | + + |
B2 | 64.48482 | 1 | 64.48482 | 24.0619 | 0.0002 | + + |
C2 | 298.6574 | 1 | 298.6574 | 111.4412 | < 0.0001 | + + |
D2 | 25.18619 | 1 | 25.18619 | 9.397988 | 0.0084 | + + |
残差 | 37.51937 | 14 | 2.679955 | |||
失拟项 | 31.64865 | 10 | 3.164865 | 2.156373 | 0.2388 | |
纯误差 | 5.87072 | 4 | 1.46768 | |||
总和 | 1973.778 | 28 |
方差来源 | 平方和 | 自由度 | 均方 | F | P | 显著性 |
---|---|---|---|---|---|---|
回归方程 | 1936.259 | 14 | 138.3042 | 51.60691 | < 0.0001 | + + |
反应温度A | 273.512 | 1 | 273.512 | 102.0584 | < 0.0001 | + + |
反应时间B | 142.761 | 1 | 142.761 | 53.26993 | < 0.0001 | + + |
异丁醇钾与甲基异丁基酮摩尔比C | 903.9352 | 1 | 903.9352 | 337.2949 | < 0.0001 | + + |
溶剂用量D | 8.619075 | 1 | 8.619075 | 3.216127 | 0.0945 | |
AB | 0.81 | 1 | 0.81 | 0.302244 | 0.5911 | |
AC | 17.1396 | 1 | 17.1396 | 6.395481 | 0.0241 | + |
AD | 2.5×10-5 | 1 | 2.5×10-5 | 9.33×10-6 | 0.9976 | |
BC | 8.4681 | 1 | 8.4681 | 3.159792 | 0.0972 | |
BD | 3.591025 | 1 | 3.591025 | 1.339957 | 0.2664 | |
CD | 0.893025 | 1 | 0.893025 | 0.333224 | 0.5729 | |
A2 | 378.1677 | 1 | 378.1677 | 141.1097 | < 0.0001 | + + |
B2 | 64.48482 | 1 | 64.48482 | 24.0619 | 0.0002 | + + |
C2 | 298.6574 | 1 | 298.6574 | 111.4412 | < 0.0001 | + + |
D2 | 25.18619 | 1 | 25.18619 | 9.397988 | 0.0084 | + + |
残差 | 37.51937 | 14 | 2.679955 | |||
失拟项 | 31.64865 | 10 | 3.164865 | 2.156373 | 0.2388 | |
纯误差 | 5.87072 | 4 | 1.46768 | |||
总和 | 1973.778 | 28 |
循环次数 | 甲基异丁基酮转化率/% | S104收率/% |
---|---|---|
新配氢氧化钾溶液 | 92.46 | 85.91 |
1 | 89.14 | 83.19 |
2 | 90.29 | 83.77 |
3 | 93.82 | 87.16 |
4 | 93.11 | 86.87 |
5 | 91.22 | 84.52 |
循环次数 | 甲基异丁基酮转化率/% | S104收率/% |
---|---|---|
新配氢氧化钾溶液 | 92.46 | 85.91 |
1 | 89.14 | 83.19 |
2 | 90.29 | 83.77 |
3 | 93.82 | 87.16 |
4 | 93.11 | 86.87 |
5 | 91.22 | 84.52 |
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