Abstract: Liquid-phase conversion of methane to more useful chemical products has advantages of mild reaction conditions，low energy consumption and less investment costs. The study of liquid-phase partial oxidation of methane to methanol is of great strategic significance for direct conversion and utilization of natural gas. Advances in research on acidic solvents，water and acetobitrile solvent for liquid-phase partial oxidation of methane to methanol was introduced. The effects of reaction mechanism，catalysts，solvent concentration on methane conversion in various media were summarized and the functions of these solvents in partial oxidation of methane in liquid phase were also discussed. Comprehensive utilization of acidic solvents’ properties and the development of novel high performance solvents with environmental friendliness，mild reaction conditions and high efficiency were important research topics for methane to methanol through liquid-phase partial oxidation.

Key words: methane, partial oxidation, methanol, solvents, catalyst, reaction, kinetics

摘要： 甲烷液相转化具有反应条件温和、能耗低、投资少等优点，研究甲烷液相部分氧化制甲醇对实现天然气的直接转化和利用具有极为重要的战略意义。本文介绍了甲烷液相部分氧化制甲醇反应中有关反应溶剂介质的研究进展，详细叙述了各种酸性介质、水以及乙腈溶剂在甲烷部分氧化制甲醇中的应用，总结了不同溶剂介质下的反应机理、催化剂、溶剂浓度等对甲烷转化的影响，探讨了溶剂在甲烷液相部分氧化中的作用，指出依据溶剂介质的性质和作用，开发环境友好、反应条件温和、转化效率高的优良新型溶剂是甲烷液相部分氧化制甲醇的重要研究方向。

关键词: 甲烷, 部分氧化, 甲醇, 溶剂, 催化剂, 反应, 动力学