Abstract: Microscopic force between hydrate particles and agglomeration of particles are critical for steady flow of hydrate slurry. This paper investigates common equipments used in researching microscopic force and agglomeration of particles，including focused beam reflectance measurement probe，particle video microscope probe，high pressure differential scanning calorimetry and micromechanical force apparatus. Measurement with micromechanical force apparatus and theoretical study have proved that the dominant adhesion force between hydrate particles is capillary bridge force，which is the main factor causing agglomeration of particles. Force balance model is used to study agglomeration of hydrate particles and calculate critical agglomeration size. This paper also summarizes agglomeration mechanisms of hydrate particles proposed by prior researchers with emphasis on physical model of contact induced-shear limited mechanism which is based on population balance model. This mechanism can well describe dynamics process of hydrate particles agglomeration. Further research and definition of microscopic forces between hydrate particles and agglomeration will have great significance for oil and natural gas transportation，and confirming influence of anti-agglomerant on natural gas hydrate particles agglomeration will be a focus of future research.

Key words: hydrate particle, adhesion force, capillary bridge force, agglomeration

摘要： 水合物颗粒微观受力和聚集是影响水合物浆稳定流动的关键，本文调研了国内外研究水合物颗粒受力和聚集常用的测量装置，主要有聚焦光束反射测量仪、颗粒图像显微镜、高压差示扫描量热仪、微机械测力装置；受力测量和理论研究证明了毛细液桥力是导致水合物颗粒聚集的主要黏附力；介绍了常用于水合物聚集特性研究的受力平衡模型，通过该模型可以计算得到水合物颗粒最大临界聚集粒径；总结了众学者提出的水合物颗粒聚集机理，并阐述了基于群体平衡模型建立的接触诱导-剪切限制聚集机理的物理模型，该模型能够很好地描述水合物颗粒的动态聚集过程；水合物颗粒微观受力和聚集机理的深入研究和明确将对石油天然气的输送具有非常重大的意义，确定防聚集对水合物聚集的影响是未来研究的重点。

关键词: 水合物颗粒, 黏附力, 毛细液桥力, 聚集特性