Construction and application of miniature reactors based on liquid marbles

doi:10.16085/j.issn.1000-6613.2020-2515

Abstract

Abstract:

Liquid marbles are liquid droplets encapsulated by hydrophobic particles at the liquid-gas interface. The non-wetting particles can not only effectively isolate the direct contact between the internal liquids and the external solid or liquid substrates, but also realize the transportation of miniature liquids in the form of rolling, reduce the friction on the surface and improve the controllability of droplets under multi-stimuli-responsive. The formation of liquid marbles triggered by multiple stimuli is desirable for their application in fields such as microfluidic transportation and miniature reactors for chemical/biological reactions. In this article, the recent research progresses on miniature reactors based on liquid marbles were summarized, including the designing approaches, constructions and applications. Current advances on remote control of liquid marbles using external stimuli and liquid marbles in liquid as a kind long-term and temperature-controlled miniature reactors were briefly introduced. Some insights into challenges and opportunities were also provided based on our own understanding of this field.

Key words: surface, chemical reactor, nanoparticle, liquid marble, stability

摘要：

液体弹珠是由微小液滴与外部非润湿性松散颗粒组成的稳定的液固复合体。非润湿性颗粒的隔离作用不仅能有效隔绝内部微量液体与外部固体或液体基底的直接接触，还能通过给予多种外界刺激使其以滚动的形式实现微量液体的运输、降低表面的摩擦及提高液滴的操控性，在微量流体控制和微型化学/生物反应器方面具有广泛的应用前景。本文介绍了近年来国内外基于液体弹珠的微型反应器基础研究进展，综述了这类新兴微流体单元的基本性质、设计与制备的典型案例，并结合本文作者课题组在多刺激响应液体弹珠、液体中液体弹珠及其作为微型化学/生物反应器应用的研究工作，对该研究领域的问题和未来前景作了展望。

关键词: 表面, 化学反应器, 纳米粒子, 液体弹珠, 稳定性

CLC Number:

ZHAO Zhijian, PU Yuan, WANG Dan. Construction and application of miniature reactors based on liquid marbles[J]. Chemical Industry and Engineering Progress, 2021, 40(11): 6145-6154.

赵志建, 蒲源, 王丹. 液体弹珠微型反应器的设计构建及应用基础[J]. 化工进展, 2021, 40(11): 6145-6154.

Figures/Tables 25

References 50

1	VIALETTO J, HAYAKAWA M, KAVOKINE N, et al. Magnetic actuation of drops and liquid marbles using a deformable paramagnetic liquid substrate[J]. Angewandte Chemie International Edition, 2017, 56(52): 16565-16570.
2	ICHIMURA K, OH S K, NAKAGAWA M. Light-driven motion of liquids on a photoresponsive surface[J]. Science, 2000, 288(5471): 1624-1626.
3	VENANCIO-MARQUES A, BARBAUD F, BAIGL D. Microfluidic mixing triggered by an external LED illumination[J]. Journal of the American Chemical Society, 2013, 135(8): 3218-3223.
4	BERNÁ J, LEIGH D A, LUBOMSKA M, et al. Macroscopic transport by synthetic molecular machines[J]. Nature Materials, 2005, 4(9): 704-710.
5	汪伟, 苏瑶瑶, 刘壮, 等. 微流控法可控构建微尺度功能材料[J]. 化工进展, 2019, 38(1): 421-433.
	WANG Wei, SU Yaoyao, LIU Zhuang, et al. Controllable microfluidic fabrication of microscale functional materials[J]. Chemical Industry and Engineering Progress, 2019, 38(1): 421-433.
6	AUSSILLOUS P, QUÉRÉ D. Liquid marbles[J]. Nature, 2001, 411(6840): 924-927.
7	CHU Y, WANG Z K, PAN Q M. Constructing robust liquid marbles for miniaturized synthesis of graphene/Ag nanocomposite[J]. ACS Applied Materials & Interfaces, 2014, 6(11): 8378-8386.
8	ZANG D Y, CHEN Z, ZHANG Y J, et al. Effect of particle hydrophobicity on the properties of liquid water marbles[J]. Soft Matter, 2013, 9(20): 5067.
9	ARBATAN T, LI L Z, TIAN J F, et al. Liquid marbles as micro-bioreactors for rapid blood typing[J]. Advanced Healthcare Materials, 2012, 1(1): 80-83.
10	MCHALE G, NEWTON M I. Liquid marbles: principles and applications[J]. Soft Matter, 2011, 7(12): 5473.
11	MIAO Y E, LEE H K, CHEW W S, et al. Catalytic liquid marbles: Ag nanowire-based miniature reactors for highly efficient degradation of methylene blue[J]. Chemical Communications, 2014, 50(44): 5923-5926.
12	LIU D H, CHOI S, CHEN B, et al. Cover picture: nontoxic membrane-active antimicrobial arylamide oligomers[J]. Angewandte Chemie International Edition, 2004, 43(9): 1033.
13	FULLARTON C, DRAPER T C, PHILLIPS N, et al. Evaporation, lifetime, and robustness studies of liquid marbles for collision-based computing[J]. Langmuir, 2018, 34(7): 2573-2580.
14	MAHADEVAN L, POMEAU Y. Rolling droplets[J]. Physics of Fluids, 1999, 11(9): 2449-2453.
15	MCELENEY P, WALKER G M, LARMOUR I A, et al. Liquid marble formation using hydrophobic powders[J]. Chemical Engineering Journal, 2009, 147(2/3): 373-382.
16	DANDAN M, ERBIL H Y. Evaporation rate of graphite liquid marbles: comparison with water droplets[J]. Langmuir, 2009, 25(14): 8362-8367.
17	MELE E, BAYER I S, NANNI G, et al. Biomimetic approach for liquid encapsulation with nanofibrillar cloaks[J]. Langmuir, 2014, 30(10): 2896-2902.
18	NGUYEN T H, HAPGOOD K, SHEN W. Observation of the liquid marble morphology using confocal microscopy[J]. Chemical Engineering Journal, 2010, 162(1): 396-405.
19	FERNANDES A M, MANTIONE D, GRACIA R, et al. From polymer latexes to multifunctional liquid marbles[J]. ACS Applied Materials & Interfaces, 2015, 7(7): 4433-4441.
20	BORMASHENKO E, POGREB R, WHYMAN G, et al. Surface tension of liquid marbles[J]. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2009, 351(1/2/3): 78-82.
21	AVRĂMESCU R E, GHICA M V, DINU-PÎRVU C, et al. Liquid marbles: from industrial to medical applications[J]. Molecules, 2018, 23(5): 1120.
22	CELESTINI F, KOFMAN R. Vibration of submillimeter-size supported droplets[J]. Physical Review E, 2006, 73(4): 041602.
23	ASARE-ASHER S, CONNOR J N, SEDEV R. Elasticity of liquid marbles[J]. Journal of Colloid and Interface Science, 2015, 449: 341-346.
24	BORMASHENKO E. Liquid marbles, elastic nonstick droplets: from minireactors to self-propulsion[J]. Langmuir, 2017, 33(3): 663-669.
25	JIN J, OOI C H, DAO D V, et al. Liquid marble coalescence via vertical collision[J]. Soft Matter, 2018, 14(20): 4160-4168.
26	CHEN Z, ZANG D, ZHAO L, et al. Liquid marble coalescence and triggered microreaction driven by acoustic levitation[J]. Langmuir, 2017, 33(25): 6232-6239.
27	LIU Z, FU X Y, BINKS B P, et al. Coalescence of electrically charged liquid marbles[J]. Soft Matter, 2016, 13(1): 119-124.
28	闫超, 李梅, 路庆华. 液体弹珠及其研究进展[J]. 化学进展, 2011, 23(4): 649-656.
	YAN Chao, LI Mei, LU Qinghua. Progress in liquid marbles[J]. Progress in Chemistry, 2011, 23(4): 649-656.
29	KIDO K, IRELAND P M, SEKIDO T, et al. Formation of liquid marbles using pH-responsive particles: rolling vs electrostatic methods[J]. Langmuir, 2018, 34(17): 4970-4979.
30	CASTRO J O, NEVES B M, REZK A R, et al. Continuous production of Janus and composite liquid marbles with tunable coverage[J]. ACS Applied Materials & Interfaces, 2016, 8(28): 17751-17756.
31	BHOSALE P S, PANCHAGNULA M V. Sweating liquid micro-marbles: dropwise condensation on hydrophobic nanoparticulate materials[J]. Langmuir, 2012, 28(42): 14860-14866.
32	LIU Z, ZHANG Y Y, CHEN C L, et al. Larger stabilizing particles make stronger liquid marble[J]. Small, 2019, 15(3): 1804549.
33	BHOSALE P S, PANCHAGNULA M V, STRETZ H A. Mechanically robust nanoparticle stabilized transparent liquid marbles[J]. Applied Physics Letters, 2008, 93(3): 034109.
34	QIN S W, WANG D, WANG J X, et al. Polyhedral oligomeric silsesquioxane-coated nanodiamonds for multifunctional applications[J]. Journal of Materials Science, 2018, 53(23): 15915-15926.
35	CHIN J M, REITHOFER M R, TAN T T, et al. Supergluing MOF liquid marbles[J]. Chemical Communications, 2013, 49(5): 493-495.
36	ZHAO Z J, LING C, WANG D, et al. Liquid marbles in liquid[J]. Small, 2020, 16(37): 2002802.
37	ZHANG L B, CHA D, WANG P. Remotely controllable liquid marbles[J]. Advanced Materials, 2012, 24(35): 4756-4760.
38	BORMASHENKO E, FRENKEL M, BORMASHENKO Y, et al. Superposition of translational and rotational motions under self-propulsion of liquid marbles filled with aqueous solutions of camphor[J]. Langmuir, 2017, 33(46): 13234-13241.
39	PAVEN M, MAYAMA H, SEKIDO T, et al. Light-driven delivery and release of materials using liquid marbles[J]. Advanced Functional Materials, 2016, 26(19): 3199-3206.
40	BORMASHENKO E, BORMASHENKO Y, GRYNYOV R, et al. Self-propulsion of liquid marbles: leidenfrost-like levitation driven by Marangoni flow[J]. The Journal of Physical Chemistry C, 2015, 119(18): 9910-9915.
41	AUSSILLOUS P, QUÉRÉ D. Properties of liquid marbles[J]. Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences, 2006, 462(2067): 973-999.
42	BORMASHENKO E, POGREB R, BALTER R, et al. Liquid marbles containing petroleum and their properties[J]. Petroleum Science, 2015, 12(2): 340-344.
43	SUN Y J, HUANG X, SOH S. Solid-to-liquid charge transfer for generating droplets with tunable charge[J]. Angewandte Chemie International Edition, 2016, 55(34): 9956-9960.
44	ZHAO Y, FANG J, WANG H X, et al. Magnetic liquid marbles: manipulation of liquid droplets using highly hydrophobic Fe₃O₄ nanoparticles[J]. Advanced Materials, 2010, 22(6): 707-710.
45	LUO X, YIN H, LI X, et al. CO₂-Triggered microreactions in liquid marbles[J]. Chemical Communications, 2018, 54(66): 9119-9122.
46	ZHAO Z J, QIN S W, WANG D, et al. Multi-stimuli-responsive liquid marbles stabilized by superhydrophobic luminescent carbon dots for miniature reactors[J]. Chemical Engineering Journal, 2020, 391: 123478.
47	HAN X, LEE H K, LEE Y H, et al. Dynamic rotating liquid marble for directional and enhanced mass transportation in three-dimensional microliter droplets[J]. The Journal of Physical Chemistry Letters, 2017, 8(1): 243-249.
48	GAO W, LEE H K, HOBLEY J, et al. Graphene liquid marbles as photothermal miniature reactors for reaction kinetics modulation[J]. Angewandte Chemie International Edition, 2015, 127(13): 4065-4068.
49	LI M S, TIAN J F, LI L Z, et al. Charge transport between liquid marbles[J]. Chemical Engineering Science, 2013, 97: 337-343.
50	WANG D, ZHU L, CHEN J F, et al. Liquid marbles based on magnetic upconversion nanoparticles as magnetically and optically responsive miniature reactors for photocatalysis and photodynamic therapy[J]. Angewandte Chemie International Edition, 2016, 55(36): 10795-10799.

[1]	ZHANG Zuoqun, GAO Yang, BAI Chaojie, XUE Lixin. Thin-film nanocomposite (TFN) mixed matrix reverse osmosis (MMRO) membranes from secondary interface polymerization containing in situ grown ZIF-8 nano-particles [J]. Chemical Industry and Engineering Progress, 2023, 42(S1): 364-373.
[2]	ZHANG Jie, BAI Zhongbo, FENG Baoxin, PENG Xiaolin, REN Weiwei, ZHANG Jingli, LIU Eryong. Effect of PEG and its compound additives on post-treatment of electrolytic copper foils [J]. Chemical Industry and Engineering Progress, 2023, 42(S1): 374-381.
[3]	LIU Yang, WANG Yungang, XIU Haoran, ZOU Li, BAI Yanyuan. Optimal carbonization process of walnut shell based on dynamic analysis [J]. Chemical Industry and Engineering Progress, 2023, 42(S1): 94-103.
[4]	WANG Shangbin, OU Hongxiang, XUE Honglai, CAO Haizhen, WANG Junqi, BI Haipu. Effect of xanthan gum and nano silica on the properties of fluorine-free surfactant mixed solution foam [J]. Chemical Industry and Engineering Progress, 2023, 42(9): 4856-4862.
[5]	LI Xuejia, LI Peng, LI Zhixia, JIN Dunshang, GUO Qiang, SONG Xufeng, SONG Peng, PENG Yuelian. Experimental comparation on anti-scaling and anti-wetting ability of hydrophilic and hydrophobic modified membranes [J]. Chemical Industry and Engineering Progress, 2023, 42(8): 4458-4464.
[6]	ZHANG Chao, YANG Peng, LIU Guanglin, ZHAO Wei, YANG Xufei, ZHANG Wei, YU Bo. Influence of surface microstructure on arrayed microjet flow boiling heat transfer [J]. Chemical Industry and Engineering Progress, 2023, 42(8): 4193-4203.
[7]	WANG Xin, WANG Bingbing, YANG Wei, XU Zhiming. Anti-scale and anti-corrosion properties of PDA/PTFE superhydrophobic coating on metal surface [J]. Chemical Industry and Engineering Progress, 2023, 42(8): 4315-4321.
[8]	LI Haidong, YANG Yuankun, GUO Shushu, WANG Benjin, YUE Tingting, FU Kaibin, WANG Zhe, HE Shouqin, YAO Jun, CHEN Shu. Effect of carbonization and calcination temperature on As(Ⅲ) removal performance of plant-based Fe-C microelectrolytic materials [J]. Chemical Industry and Engineering Progress, 2023, 42(7): 3652-3663.
[9]	ZHANG Kai, LYU Qiunan, LI Gang, LI Xiaosen, MO Jiamei. Morphology and occurrence characteristics of methane hydrates in the mud of the South China Sea [J]. Chemical Industry and Engineering Progress, 2023, 42(7): 3865-3874.
[10]	LU Yang, ZHOU Jinsong, ZHOU Qixin, WANG Tang, LIU Zhuang, LI Bohao, ZHOU Lingtao. Leaching mechanism of Hg-absorption products on CeO₂/TiO₂ sorbentsin syngas [J]. Chemical Industry and Engineering Progress, 2023, 42(7): 3875-3883.
[11]	WU Zhanhua, SHENG Min. Pitfalls of accelerating rate calorimeter for reactivity hazard evaluation and risk assessment [J]. Chemical Industry and Engineering Progress, 2023, 42(7): 3374-3382.
[12]	XIE Zhiwei, WU Zhangyong, ZHU Qichen, JIANG Jiajun, LIANG Tianxiang, LIU Zhenyang. Viscosity properties and magnetoviscous effects of Ni_0.5Zn_0.5Fe₂O₄ vegetable oil-based magnetic fluid [J]. Chemical Industry and Engineering Progress, 2023, 42(7): 3623-3633.
[13]	YANG Jingying, SHI Wansheng, HUANG Zhenxing, XIE Lijuan, ZHAO Mingxing, RUAN Wenquan. Research progress on the preparation of modified nano zero-valent iron materials [J]. Chemical Industry and Engineering Progress, 2023, 42(6): 2975-2986.
[14]	DONG Xiaoshan, WANG Jian, LIN Fawei, YAN Beibei, CHEN Guanyi. Exsolved metal nanoparticles on perovskite oxides: exsolution, driving force and control strategy [J]. Chemical Industry and Engineering Progress, 2023, 42(6): 3049-3065.
[15]	XU Guobin, LIU Honghao, LI Jie, GUO Jiaqi, WANG Qi. Preparation and properties of ZnO QDs water-based inkjet fluorescent ink [J]. Chemical Industry and Engineering Progress, 2023, 42(6): 3114-3122.