Abstract: In this study,benzothiazolium methanesulfonate([HBth] [CH₃SO₃]),as a kind of functional ionic liquid,was used for extraction of total flavonoids from Broussonetia papyrifera leaves for the first time.The content of total flavonoids was measured using Al(NO₃)₃-NaNO₂ colorimetric method.Based on the single factor experiment,the effect of the concentration of ionic liquid,volume fraction of ethanol,extraction temperature,extraction time,solid-liquid ratio on the extraction yield of total flavonoids were examined.As a result,about 0.4685 mg of total flavonoids could be obtained from 1.0 g of raw material under the optimum conditions.Compared with traditional extraction technology,this new preparative method was simple and efficient,which is promised to replace the traditional methods with further study.

Key words: ionic liquid, Broussonetia papyrifera leaves, total flavonoids, extraction technology

摘要： 以构树叶为研究对象，研究了离子液体苯并噻唑甲烷磺酸盐在总黄酮提取工艺上的应用，采用Al（NO₃）₃-NaNO₂比色法测定了构树叶中总黄酮的含量。通过单因素试验，以构树叶中总黄酮提取率为指标，探讨了离子液体浓度、乙醇体积分数、提取温度、提取时间、料液比对构树叶中总黄酮提取率的影响。实验结果表明在离子液体浓度0.5mol/L、乙醇体积分数60%、提取温度60℃、提取时间20 min、料液比1：20的工艺条件下，测得构树叶总黄酮含量为0.4685mg/g。该提取工艺操作简单、合理、提取效率较高。

关键词: 离子液体, 构树叶, 总黄酮, 提取工艺