化工进展 ›› 2017, Vol. 36 ›› Issue (02): 672-682.DOI: 10.16085/j.issn.1000-6613.2017.02.038

• 精细化工 • 上一篇    下一篇

生物基芳香平台化合物2,5-呋喃二甲酸的合成研究进展

王静刚, 刘小青, 朱锦   

  1. 中国科学院宁波材料技术与工程研究所, 浙江 宁波 315201
  • 收稿日期:2016-03-01 修回日期:2016-09-28 出版日期:2017-02-05 发布日期:2017-02-05
  • 通讯作者: 刘小青,研究员,研究方向为生物基高分子材料。E-mail:liuxq@nimte.ac.cn。
  • 作者简介:王静刚(1982-),男,博士研究生,主要研究方向2,5-呋喃二甲酸及其聚合物的合成研究。
  • 基金资助:
    国家自然科学基金(51373194)及国家重点科技支撑项目(2015BAD15B08)。

Research progress on the synthesis of bio-based aromatic platform chemical 2,5-furandicarboxylic acid

WANG Jinggang, LIU Xiaoqing, ZHU Jin   

  1. Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, Ningbo 315201, Zhejiang, China
  • Received:2016-03-01 Revised:2016-09-28 Online:2017-02-05 Published:2017-02-05

摘要: 生物基芳香平台化合物2,5-呋喃二甲酸(2,5-FDCA)有望替代现有的石油基单体对苯二甲酸用于高性能高分子材料的合成。如何通过高效、廉价的路线制备2,5-FDCA已经成为近几十年的研究热点。本文系统地介绍了从5-羟甲基糠醛(HMF)、糠酸、呋喃、二甘醇酸或己糖二酸制备2,5-FDCA的各种方法,并重点介绍了HMF的直接氧化法、贵金属氧化法、非贵金属氧化法和生物酶氧化法合成2,5-FDCA。在比较了现有各种路线优缺点的基础上,认为HMF路线是2,5-FDCA规模化制备最有希望的路线,长远发展应朝着以纤维素为起始原料的方向,打通纤维素到糖的关键制备技术。

关键词: 2,5-呋喃二甲酸, 生物基, 平台化合物, 合成, 进展

Abstract: 2,5-Furandicarboxylic acid(2,5-FDCA) is a promising bio-based aromatic platform chemical for the synthesis of high performance polymers and has been regarded as the most suitable alternative to the petroleum-derived terephthalic acid. The synthesis of 2,5-FDCA through efficient and low cost route has been a hot subject since last decade. In this review article,the popular starting materials,including 5-hydroxymethyl furfural(HMF),furoic acid,furan,diglycolic acid,and hexaric acid,for the fabrication of 2,5-FDCA,are introduced in detail. Perspectives are given based on the comparison of different synthetic routes. The most popular synthetic route is based on HMF by either directly oxidation,noble metal oxidation,non-noble metal oxidation or enzyme catalysis oxidation. This method is considered as the most promising one to achieve large scale preparation of 2,5-FDCA. More importantly,development of novel technology for the conversion of cellulose to glucose is critical to produce large amount of low cost HMF.

Key words: 2,5-furandicarboxylic acid, bio-based, platform chemical, synthesis, progress

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