Abstract: Considering the refractory features of antibiotic industrial wastewater，especially difficulty of biodegradation for the effluent of the mixed industrial wastewater after the secondary biochemical treatment ozone pretreatment + flocculation + BAF combined process was applied in this research. The results showed that the removal rate of COD treated by BAF process alone was 4.7% failing to meet the effluent standards. Ozonation can changes the structure and property of some organic components in wastewater，making further biodegradation possible. Ozone pretreatment can improve the biodegradability of effluent after secondary biochemical treatment and improve treatment efficiency of BOD. The optimal ozone concentration was 20mg/L. The average removal rate of COD，NH3-N and TP was 40.7%，34.4% and 79.1%，respectively. The concentration of COD，NH3-N，and TP in effluent achieved the first grade of Comprehensive Discharge Standard for Sewage （GB8978—1996）. This combined process provided a new way for the advanced treatment of effluent of refractory antibiotic industrial wastewater after secondary biochemical treatment.

Key words: ozone pretreatment, flocculation, biological aerated filter, antibiotic, effluent after secondary biochemical treatment, advanced treatment

摘要： 针对抗生素类工业废水难处理特点，特别是混合工业废水经二级生化处理后的尾水具有很难生化的特质，因此对二级生化处理后的尾水采用“臭氧预处理+絮凝沉淀+BAF”组合工艺进行深度处理。结果表明：依靠单纯BAF工艺处理COD去除效率平均仅为4.7%，无法达标，必须经臭氧氧化作用改变废水中某些有机物的结构和特性，使其发生开环、断链，才能进一步生物降解；臭氧预处理有效提高了二级生化出水的可生化性，且臭氧对BOD5处理效率随臭氧投加量的增加而提高，臭氧最佳投加量为20mg/L；该组合工艺对COD、NH3-N 和TP的平均去除效率为40.7%、34.4%和79.1%，出水COD、NH3-N 和TP等指标均能达到《污水综合排放标准》（GB8978—1996）的一级排放标准。该组合工艺为难生物降解的抗生素类制药为主的混合工业废水二级出水的深度处理提供了新途径。

关键词: 臭氧预处理, 絮凝沉淀, 曝气生物滤池, 抗生素, 二级生化出水, 深度处理