Abstract: In this work，the synthesis procedure of sodium 2,3-butanedione mono-oximate was monitored by IR-online. According to the change of characteristic IR spectra of 2-butanone (1719cm?1)，2,3-butanedione mono-oxime (1693cm?1，3249cm?1)，ethanol(1026cm?1) and sodium 2,3-butanedione mono-oximate(1643cm?1)，the changes of all components’ concentration in the solution was investigated and the reaction procedure was understood. The end point of the synthesis reaction could be determined simply and rapidly by IR-online，therefore the reaction procedure could be controlled by this method.

Key words: IR-online, ketoxime, reaction procedure, synthesis

摘要： 利用在线红外光谱对2,3-丁二酮单肟钠盐的合成反应进行了在线监测，通过监测反应物2-丁酮（1719cm?1）、中间体2,3-丁二酮单肟（1693cm?1和3249cm?1）和乙醇（1026cm?1）以及最终产物2,3-丁二酮单肟钠盐（1643cm?1）特征峰的变化，推断了反应体系中各组分浓度的变化规律，从而比较清楚地了解了该反应的进程。结果表明，在线红外光谱能够快速、简便、准确地确定出反应结束时间，从而达到对合成反应过程进行控制的目的。

关键词: 在线红外光谱, 酮肟, 反应过程, 合成