岩藻黄素的提取技术和应用现状

doi:10.16085/j.issn.1000-6613.2025-0496

摘要/Abstract

摘要：

岩藻黄素（fucoxanthin）是一种存在于藻类、海洋浮游生物和水生贝壳类等动植物中的色素，具有优异的抗氧化、抗肥胖、抗炎、抗癌等生物活性作用，在各个领域具有巨大潜力。本文介绍了岩藻黄素提取前预处理的方法，回顾了传统溶剂溶浸提取法，介绍了新型和辅助提取技术，并总结了提取过程的溶剂选择，提出了新型溶剂的应用建议，同时讲述了提纯工艺技术与制剂工艺，对岩藻黄素的工业潜力与应用前景进行了展望。目前，岩藻黄素的产业化生产受限于成本与环保的问题，且近年相关研究积累较少，但国内外有关岩藻黄素性能开发的研究逐渐增多，为驱动岩藻黄素产业化研究与开发提供动力。本文基于以上背景，认为岩藻黄素是一种具有开发潜力的物质，对岩藻黄素的提取技术与应用现状进行了总结，对其未来规模化产业化升级提供理论参考。

关键词: 岩藻黄素, 提取技术, 提纯技术, 产业化, 下游工艺

Abstract:

Fucoxanthin is a pigment found in plants and animals such as algae, marine plankton and aquatic shellfish, exhibiting remarkable bio-active effects including antioxidant, anti-inflammatory, anticancer, anti-obesity and anti-angiogenesis properties. These findings render it a promising candidate for applications in various fields. This review introduced a series of methodologies including pretreatment techniques, traditional, novel and auxiliary extraction technologies and the solvent selection, provided a detailed description of the purification process technology and preparative process, and addressed the industrial potential and development prospects of fucoxanthin. Presently, the industrial production of fucoxanthin was constrained by economic and environmental concerns. Despite the paucity of related research in recent years, there had been a gradual increase in researches focused on the exploration of fucoxanthin properties, and this growing body of research signified a significant potential for the advancement and industrialization of fucoxanthin. In light of the aforementioned background, this review posited that fucoxanthin was a promising material for development, and it provided a comprehensive overview of the extraction technology and current applications of fucoxanthin. In principle, this review aimed to provide insights for the future scale-up of fucoxanthin for industrialization and upgrading.

Key words: fucoxanthin, extraction technology, purification technology, industrialization, downstream process

中图分类号:

TQ464

张育新, 邓子洋, 王灿, 曾丹. 岩藻黄素的提取技术和应用现状[J]. 化工进展, 2025, 44(S1): 422-433.

ZHANG Yuxin, DENG Ziyang, WANG Can, ZENG Dan. Recent advances of extraction technology and application of fucoxanthin[J]. Chemical Industry and Engineering Progress, 2025, 44(S1): 422-433.

图/表 5

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技术类型	提取率/mg·g^-1	溶剂用量	能耗	环保性	参考文献
传统溶剂浸取	1.5~2.5	高	高	中等（溶剂残留）	[24,26]
超声辅助提取	2.0~2.8	中	中	高（溶剂需求量低）	[31,37]
超临界CO₂萃取	8.0~12.0	低	中高	高（无毒）	[40,43-44]
电技术辅助提取	10.0~16.0	低	低	高（无溶剂）	[53-54]

技术类型	提取率/mg·g^-1	溶剂用量	能耗	环保性	参考文献
传统溶剂浸取	1.5~2.5	高	高	中等（溶剂残留）	[24,26]
超声辅助提取	2.0~2.8	中	中	高（溶剂需求量低）	[31,37]
超临界CO₂萃取	8.0~12.0	低	中高	高（无毒）	[40,43-44]
电技术辅助提取	10.0~16.0	低	低	高（无溶剂）	[53-54]