Abstract: Bio-effects of non-thermal plasma include lethality of microorganisms and stimulation of mammalian cells，which brings up a series of techniques in disinfection and clinical medicine. In this paper，the applications of non-thermal plasma in medical device sterilization，water and air cleaning，as well as food and package treatment are reviewed. Commercialized plasma sterilizer for medical devices can be classified into vacuum and atmospheric pressure，the volume of the former is much larger while the latter is more simple and easy to operate. For disinfection of water，air and food，it is not yet commercialized due to its energy consumption，efficiency or chemical residues. In the last decade，the developed plasma sources and techniques for medicine are successfully applied to treatment of decayed tooth，skin，wound，and cancer，with some of them approved for clinical practice. In the future，the research focus will be identifying the interactions between plasmas and cells，and developing more effective and practical equipment for different applications.

Key words: non-thermal plasma, medicine, disinfection, water treatment, air cleaning

摘要： 低温等离子体的生物学效应包括对微生物的致死作用和对动物细胞的刺激作用，分别造就了一批灭菌技术和临床医药技术。本文介绍了等离子体灭菌技术在医疗器械、水和空气净化、食品和包装材料处理等方面的应用。其中已商业化的医疗器械灭菌器主要分低气压和常压两种，低气压等离子体灭菌器的灭菌体积较大，常压等离子体灭菌器的优点则是结构简单和便于操作。等离子体灭菌技术用于水、空气、食品等领域由于能耗、效率、化学残留等问题尚未商业化。在医药技术方面，近十年来开发的等离子体技术和装备成功运用于龋齿、皮肤、伤口、癌症等的处理，部分已进入临床应用。将来的研究重点在于明确等离子体与细胞之间的相互作用机理，并开发出更高效、实用的用于各相关行业的等离子体技术和装备。

关键词: 低温等离子体, 生物医药, 消毒灭菌, 水处理, 空气净化