Abstract:

Supercritical anti-solvent（SAS）technology is a novel technique for the preparation of micro- and nano-particles，and has been largely applied in pharmaceuticals，superconductors，coloring matters，explosives and polymers. The supercritical anti-solvent process and its application in the preparation of single and multi-composition inorganic oxide nanoparticles were reviewed. The particle formation mechanism in the SAS process was summarized. The future development of the SAS technology was also proposed.

摘要：

超临界抗溶剂技术是一种新型的超细微粒制备技术，在药物、超导、颜料、炸药和聚合物等领域已有广泛的应用。本文主要介绍了超临界抗溶剂过程和该技术在单组分和多组分无机氧化物纳米粒子制备上的应用，并对超临界抗溶剂微粒成形机理的研究现状和微粒的成形机理进行了简要的概括总结。最后对超临界抗溶剂微粒化技术的发展做了进一步展望。