Abstract:

1,3-Propanediol is a chemical intermediate with a wide range of applications. The synthesis of new polyester PTT is a major one among them. Separation and recovery of 1,3-propanediol from a fermentation broth is one of technological keys and difficult problems in biological production of 1,3 - propanediol. In this paper，the state of art for the downstream processing and purification of biologically produced 1,3-propanediol is outlined and compared in detail. The separation methods discussed include evaporation and distillation，solvent extraction，reactive extraction，molecular sieve adsorption and the cationic exchange resin chromatography. The outlook on the industrial biological production of 1,3-propanediol is also prospected.

摘要：

1,3-丙二醇是一种具有广泛用途的化工中间体，主要用于合成新型聚酯PTT。从发酵液中分离回收产物是生物法生产1,3-丙二醇的技术关键和难点之一，本文对1,3-丙二醇的分离方法及技术研究进展作了概述，较详细地比较了蒸发精馏、溶剂萃取、反应萃取、分子筛吸附、离子交换色谱分离等分离方法的特点和存在的问题。分析当前的研究现状，展望了生物法生产1,3-丙二醇的工业前景。