Abstract: 3-Hydroxypropionaldehyde (3-HPA） is a potential valuable chemical. The methods of 3-HPA preparation include ethylene oxide process，acrolein hydration and biosynthesis. With the brief introduction of properties and usages of 3-HPA，the paper presents the technological processes and research status of the chemical preparation for 3-HPA. Besides，the paper focuses on the principle，strains and process route of biosynthesis of 3-HPA. In the end，the future development of 3-HPA production is prospected.

摘要： 3-羟基丙醛是一种潜在的重要化工原料，其制备方法有环氧乙烷羰基合成法、丙烯醛水合法和生物合成法。本文首先简述3-羟基丙醛的基本性质和用途，然后详细介绍了化学法制备3-羟基丙醛的工艺和研究现状，重点阐述了生物法制备3-羟基丙醛的原理、菌种和工艺路线，最后对3-羟基丙醛制备工艺的研究方向进行了展望。