Abstract:

Polyaspartic acid (PASP) hydrogel has attracted the attention of many researchers due to its biocompatibility, biodegradability, water absorption and retention. In this paper, the synthesis methods of PASP hydrogels were reviewed, and their advantages and disadvantages were compared. On this basis, the water phase homogeneous cross-linking process developed by our group was introduced, which has the advantages of low pollution and low cost, and initially industrial production was realized. The water absorption ratio of the product can reach 300―1000g/g. In addition, the blending/copolymerization modification of PASP hydrogel and its application in agriculture, ecological restoration and environmental protection were reviewed. The structural designability of PASP and its related research in biomedical field were highlighted. Among them, our group continued to carry out its research as a water-retaining agent, and obtained good experimental results, which provided a useful reference for large-scale application. Finally, this paper summarizes the problems that need to be solved in PASP hydrogels for the correlation of PASP performance, synthesis process and application fields. The elaboration of this paper will provide guidance and reference for the research, synthesis and application of PASP hydrogel.

Key words: polyaspartic acid, hydrogel, preparation, application

摘要：

聚天冬氨酸（PASP）水凝胶由于其良好的生物相容性、生物降解性及吸水、保水性引起了众多科研工作者的关注。本文首先综述了PASP水凝胶的合成方法，并对比了各自的优势和不足。在此基础上，介绍了本文作者课题组开发的水相均相交联工艺，此工艺具有污染小、成本低的优势，并初步实现了工业化生产，产品的吸水倍率可达300~1000g/g。此外，本文还综述了PASP水凝胶的共混/共聚改性及其在农业及生态修复、环境保护的应用，并着重介绍了PASP的结构可设计性及其在生物医学领域的相关应用研究。其中，本文作者课题组针对PASP水凝胶的吸水保水特性，持续开展了其作为农林保水剂的研究，并得到了良好的试验结果，为大规模应用提供了有益的参考。最后针对PASP性能、合成工艺和应用领域的关联性，归纳了PASP水凝胶亟待解决的问题。本文的阐述将为PASP水凝胶的合成、应用和推广等研究工作提供指导和参考。

关键词: 聚天冬氨酸, 水凝胶, 制备, 应用