Abstract: Ferrocene derivatives, due to their excellent electrochemical activity, thermal and photochemical stability, have drawn more and more attention in materials and pharmaceutical fields. Ferrocene boronic acid as a raw material for the preparation of ferrocene derivatives has a wide range of applications in the synthetic reaction. This paper reviews and summarizes the research progress of the synthetic reactions involved ferrocene boric acid at home and abroad in recent years. The reactions were investigated comprehensively from the substrate type, reaction condition, yield and mechanism. This kind of reactions have wide application prospect in the fields of drug and catalyst synthesis, preparation of metal organic materials, development of optical devices and construction of molecular motor nanometer system. Finally, in the view of existing problems such as the participation of heavy metals, harsh reaction conditions, and poor reaction yields, this paper points out that the green, inexpensive and efficient reaction system is the future development direction. The vast majority of reaction involved ferrocene boric acid was coupling reaction; the number of other reaction types was relatively few. With deepening of the research, more and more reactions involved ferrocene boric acid will be developed, which will become an important means of organic synthesis.

Key words: ferrocene boronic acid, ferrocene derivatives, coupling reactions, addition reactions

摘要： 二茂铁衍生物由于具有优良的电化学活性、热和光化学稳定性，在材料和医药领域越来越受到关注。二茂铁硼酸作为二茂铁衍生物的制备原料，在合成反应中具有广泛的应用。本文回顾和总结了近些年来国内外利用二茂铁硼酸进行合成反应的研究现状，从反应底物类型、条件、产率和机理对反应进行了全面的分析，指出了该类反应在药物以及催化剂的合成、金属有机材料制备、光学器件的开发和分子马达纳米系统的构建等领域具有广阔的应用前景。最后，针对反应存在的需要重金属参与、收率不高和反应条件苛刻等问题，提出了绿色、廉价、高效的反应体系是其未来的发展方向。二茂铁硼酸参与的合成中绝大多数为偶联反应，其他反应类型相对较少；随着研究的深入，更多二茂铁硼酸参与的反应将会被开发出来，成为有机合成化学的重要手段。

关键词: 二茂铁硼酸, 二茂铁衍生物, 偶联反应, 加成反应