Abstract: The status,the research framework and the development trends of the biorefineries in and abroad were discussed in this paper. Succinic acid was regarded as the one with better flexibility and capability for wide application in synthesizing the butanediol and its derivatives. Glycerol was of great value in the synthesis of propanediol,epichlorohydrin,latic acid etc. Key research fields were thus listed with a focus on the application of the succinic acid and glycerol as the "platform molecules". Meanwhile,based on the review on lignocelluloses converting techniques,a new progress about catalytic decomposition and fermentation of lignocelluloses was introduced. Furthermore,the existing challenges and limitations of the overseas biorefineries on efficiency,feedstock sources,product separation and region restriction were analyzed in depth. The further anticipation of development prospect of biorefinery in expanding material sources and featured bio-based chemicals also offers a reference for the future development of the domestic biorefinery.

Key words: biological engineering, biorefinery, succinic acid, grycerol, lignocellulose

摘要： 介绍了国内外生物炼制厂发展现状、研究框架及发展趋势。列举了生物炼制产业未来的重点研究领域，重点阐述了琥珀酸和甘油作为生物炼制厂"平台分子"的应用状况。琥珀酸作为平台分子被认为具有更好的灵活性，在丁二醇及其衍生物合成方面具有广泛的应用前景；甘油在丙二醇、环氧氯丙烷、乳酸等化工产品合成方面具有重要价值。文中回顾了木质纤维素转化的相关研究，介绍了木质纤维素在催化分解和发酵方面的较新进展。较为全面地分析了近年来国外生物炼制厂在生产效率、原料来源、产品分离、地域限制等方面的局限性，展望了未来生物炼制厂在拓展原料来源和开发生物基特色产品等方面的发展趋势，为国内生物炼制厂的发展提供了参考。

关键词: 生物工程, 生物炼制, 琥珀酸, 甘油, 木质纤维素