Abstract: A synthesis process of 4-methoxystyrene by NaBH₄ reduction of p-acetanisole and zeolite catalytic dehydration of 1-(4-methoxyphenyl)ethanol was developed. An optimized synthesis process was proposed with vaporization temperature of 270℃,reaction temperature of 280℃,vacuum of -0.09MPa and feed rate of 1mL/min,and with a yield of 85% [based on 1-(4-methoxyphenyl)ethanol] and GC purity of 95%. The product was characterized by IR, ¹H NMR and MS. The synthesis process of 4-methoxystyrene with mild reaction condition,simple control and availability of raw materials would have potential for industrial production.

Key words: p-acetanisole, 4-methoxystyrene, zeolite catalysts

摘要： 研究了以对甲氧基苯乙酮为原料,经硼氢化钠还原为1-(4-甲氧基苯基)乙醇,在管式反应器中经分子筛催化裂解脱水合成对甲氧基苯乙烯的新工艺,得到优化的工艺条件:汽化温度270℃,反应温度280℃,真空度-0.09MPa,进料速度1mL/min.目标产物经红外光谱(IR)、核磁共振波谱(¹H NMR)和质谱(MS)等表征.同时用色谱(GC)对产物进行了定量分析,在优化条件下对甲氧基苯乙烯纯度大于95%,收率达85%[以1-(4-甲氧基苯基)乙醇计].该路线原料易得,反应条件温和,操作控制简便,适合进一步工业化研究.

关键词: 对甲氧基苯乙酮, 对甲氧基苯乙烯, 分子筛催化剂