关键词: 植物天然产物, 微生物细胞工厂, 途经重构, 合成生物学

Abstract: Plant natural products equipped with versatile physiological activities such as anti-virus, anti-inflammatory, anti-tumor, and liver protection, are widely used in health food, pharmaceuticals and other human health-related fields. However, the current production pattern of natural plant products was dominated by phytoextraction, which not only consume a large amount of plant resources, but the generation of vast organic solid waste also brings severe environmental and ecological concerns. As the international community pays more attention to sustainable development, the use of microbial cell factories to synthesize plant natural products, which is economically feasible and environmentally friendly, have become current research hotspots. This article reviews the research progress of pathway design and reconstruction for synthesizing plant natural products by microbial cell factories.

Key words: Plant natural products, Microbial cell factories, Pathway reconstruction, Synthetic biology