Abstract: Pulsating heat pipe has got great attention in the field of heat pipes due to its simple structure，low cost，excellent thermal performance and good compatibility. It has already shown very high development potential for electronics cooling，freezing technology and thermal control applications in space and avionics. This paper introduces the structure and principle of pulsating heat pipe. A comprehensive review of experiments，numerical simulation and applications available so far is presented. Future development of pulsating heat pipe is how to achieve diversification，miniaturizatione and practical application.