微纳米流控芯片传感器研究及其在环境检测中的应用

摘要/Abstract

摘要： 与传统生物传感器相比,微纳米流体生物传感器在减少样品使用剂量,实现高通量、快速检测、特异性检测,以及简化实验操作等方面都显示出无可比拟的优越性。本文所涉及的微纳米的生物传感器大体上可以分成两大类:第一类是常规的微纳米流控生物传感器(简称微流控芯片),通常以硅、玻璃以及高分子聚合物作为基材;第二类则是最近兴起的试纸条生物传感器,其基材为纸质。本文从以下几方面对当前微流体生物传感器的研究与应用进行总结:微流体生物传感器的基本理论,材料特征与制作工艺方面,以及在环境监测领域的典型性应用,最后对基于各种不同工艺技术制作的微流体生物传感器在技术方面的难点和应用上的局限性进行简要分析。

关键词: 微流控芯片, 试纸条生物传感器, 环境监测

Abstract: Compared to traditional biosensors, micro/nano-fluidic based biosensors show great advantages in reducing sample volume, rapid and specific detection,high throughput, and easy manipulation.These superiorities have paved the way for micro/nano-fluidic based biosensors to become real world products finally.The small scale biosensors are categorized into two broad classes here, which are the conventional micro/nano-fluidic based biosensors and microfluidic paper-based analytical devices (μPADs) emerged recently.This chapter starts with a brief introduction of the current state-of-the-art micro/nano-fluidic based biosensors, followed by the relevant underlying theories, characterisation of materials, development of fabrication techniques and some typical applicationsin environmental monitoring.The limitations and perspectives of the biosensors based on different techniques are simply suggested.

Key words: micro/nano-fluidic based biosensors, microfluidic paper-based analytical devices, environmental monotoring

余明博, 陈斌, 李卓. 微纳米流控芯片传感器研究及其在环境检测中的应用[J]. 化工进展, 2015, 34(s1): 182-186.

YU Mingbo, CHEN Bin, LI Zhuo. Micro/nano-fluidic biosensors applied in environmental monotoring[J]. Chemical Industry and Engineering Progree, 2015, 34(s1): 182-186.

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