Abstract:

The solute concentration is one of the key factors in chemical process study．The difficulty in obtaining highly accurate concentration measurements is a significant limitation to the development of reliable techniques for the modeling，monitoring，and optimizing of chemical process．In this work，attenuated total reflection Fourier Transform Infrared Spectroscopy（ATR-FTIR）is coupled with partial least square（PLS）to provide a solute concentration calibration model，in which the IR absorbances constitute the prediction variables of PLS and the concentration is  the prediction outputs．The a model is tested by a multicomponent system，the esterification of ethylparaban．Results show that the model can give reliable on-line solute concentration measurements with enough accuracy for online monitoring．