Abstract: Porous materials especially those with mesoporosity have attracted a great deal of attention owing to their potential applications. Recent years，a lot of substances have been used as templates or pore-forming agents to synthesize mesoporous materials，such as organic small molecules，ionic liquid and silica sources.These non-surfactant templating routes to mesoporous materials exhibit many advantages comparing to the traditional surfactant methods. Here we report the progress in the synthesis of silica-based mesoporous materials using non-surfactant structure-directing agents.