化工进展

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一步法提取石蒜中加兰他敏和石蒜碱

李 霞,熊远福,蒋利华,祝红福,文祝友   

  1. 湖南农业大学应用化学系;湖南农业大学动物科技学院
  • 出版日期:2008-06-05 发布日期:2008-06-05

Extraction of galanthamine and lycorine from Lycoris Herb.with one-step method

LI Xia,XIONG Yuanfu,JIANG Lihua,ZHU Hongfu,WEN Zhuyou   

  1. Department of Applied Chemistry,Hunan Agricultural University;College of Animal Science and Technology,Hunan Agricultural University
  • Online:2008-06-05 Published:2008-06-05

摘要: 采用正交实验法对石蒜中加兰他敏和石蒜碱的一步法提取工艺进行研究,考察乙醇质量分数、提取温度、固液比及提取时间对石蒜中加兰他敏和石蒜碱得率的影响。结果表明,在浸提3次条件下,最佳工艺条件为:75%乙醇、提取温度65 ℃、提取时间4 h、固液比1∶6 (g/mL),加兰他敏和石蒜碱的得率分别为0.04793%和0.03643%。

Abstract: The optimum extraction process for simultaneous extraction of galanthamine and lycorine from Lycoris Herb. was studied with orthogonal design,and the influences of ethanol volume fraction,temperature,ratio of extracted material to solvent and time were investigated. Optimum extraction conditions were determined as follows: 75% ethanol at 65 ℃ in 4 hours and the solid to liquid ratio 1∶6 (g/mL),extracting for three times. The extraction rates of total galanthamine and lycorine were 0.04793% and 0.03643% respectively .

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