Abstract: The effect of three kinds of gas spargers，including ring gas sparger，micro-orifice gas sparger Ⅰ and micro-orifice gas sparger II on oxygen mass transfer in non-Newtonian fluid was studied. The effect of micro-orifice spargers on power consumption，gas hold-up ε，oxygen mass transfer coefficient KLα and specific oxygen mass transfer coefficient of power input per volume Eo2 was specially investigated. Their results were compared with the values of ring gas sparger. Both KLα and Eo2 of two micro-orifice spargers were higher than those of ring gas sparger. The new gas spargers had superior mass transfer and mixing performance. It is beneficial to increasing oxygen concentration in non-Newtonian fluid.