化工进展

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α-羟基乙酸合成与分析方法综述

胡基埂   

  1. 浙江工业大学生物与环境工程学院
  • 出版日期:2007-04-25 发布日期:2007-04-25

Advance in production and analysis of α-hydroxyacetic acid

HU Jigeng   

  1. College of Biological & Environmental Engineering,Zhejiang University of Technology

  • Online:2007-04-25 Published:2007-04-25

摘要: α-羟基乙酸是一种重要的大宗精细化工中间体,广泛应用于黏合剂、金属清洗、生物降解材料、染色、纺织,而且是个人护理产品的重要组成成分。化学法生产羟基乙酸存在原料消耗大、产品收率低、环境污染严重等缺点;生物法合成羟基乙酸条件温和、底物转化率高,为绿色合成羟基乙酸提供强有力的技术支持。文章比较了各种羟基乙酸定性及定量分析方法,综述了羟基乙酸分离方法,特别是溶剂萃取和协同萃取效应。最后,分析了羟基乙酸的开发前景。

Abstract: α-hydroxyacetic acid is one of the most important bulk fine chemicals,extensively used in adhesives,metal cleaning,biodegradable polymers,dyeing,textiles,and as a component in personal care products. The advantages of α-hydroxyacetic acid biosynthesis over traditional chemical conversion are wide range of reaction condition,high conversion ratio and green process. The review highlights the technical developments in the identification,quantification and separation of α-hydroxyacetic acid,especially solvent extraction and synergistic extraction. Finally,the developmental prospect of α-hydroxyacetic acid is presented.

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