Abstract: Mesoporous silica SBA-15 has excellent physicochemical characteristics and structure properties，but it has no catalytic active sites because SBA-15 is composed of pure silica，and needs to be modified to introduce catalytic active sites. The recent progress of modification of mesoporous silica SBA-15 is reviewed in terms of three aspects，metal modified SBA-15 catalysts，acid modified SBA-15 catalysts and oxides modified SBA-15 catalysts. The effect of metal nanoparticles preparation on the catalytic properties is discussed.