Abstract: The biocompatible and biodegradable poly(β-hydroxybutyrate) can be used as medical material，wrapper and optics datum to partly replace current plastics. However，the high crystallization and inferior process restrict the application of poly(β-hydroxybutyrate). The advances on modification of poly(β-hydroxybutyrate)(PHB) is reviewed. The modification methods and performance of PHB copolymer are summarized. Reactive polymer blending is a useful method to improve the miscibility of PHB blends，and the modification based on PHB macromer reaction，reactive polymer blending and interpenetrating network technology represents the new trends of PHB modification.
chemical modification