Abstract: Preparation of levulinic acid from hydrolysis of Salix psammophila catalyzed by sulfuric acid as catalyst was studied in this paper. The effects of catalyst concentration，reaction time，reaction temperature，liquid-solid ratio on the yield of levulinic acid were investigated. By orthogonal tests，the optimum hydrolysis reaction conditions were as follows：reaction temperature 200℃，reaction time 90 min，catalyst concentration 9%，liquid-solid ratio(mL∶g) 15∶1，the highest yield of levulinic acid was 18.80%，the order of the factors was obtained according to the degree to which they could affect hydrolysis reaction as follows：reaction time > catalytic concentration > reaction temperature > liquid-solid ratio. 335 weak basic anion-exchange resin was used for separation and purification of hydrolysis mixed solution，under the static conditions of adsorption temperature 35 ℃，amount of resin 15 g，eluent concentration (HCl) 0.5 mol/L，recovery of levulinic acid was 95.35%.

Key words: Salix psammophila, levulinic acid, anion-exchange resin, orthogonal tests, separation and purification

摘要： 以沙柳为原料，硫酸为催化剂，考察了催化剂浓度、反应时间、反应温度、液固比对沙柳水解制备乙酰丙酸得率的影响，通过正交实验方法得到最佳的水解反应条件为：反应温度200 ℃，反应时间90 min，催化剂质量分数9%，液固比（mL∶g）15∶1，乙酰丙酸的最高得率为18.80%；各因素对水解反应影响的大小顺序为：反应时间＞催化剂浓度＞反应温度＞液固比。在静态条件下，用335弱碱性阴离子交换树脂对水解液进行分离提纯，在附吸温度为35 ℃、树脂投料量为15 g、盐酸洗脱剂浓度为0.5 mol/L时，乙酰丙酸的回收率为95.35%。

关键词: 沙柳, 乙酰丙酸, 阴离子交换树脂, 正交实验, 分离提纯