Abstract: Per-O-acetyl glucopyranose is an important carbohydrate compound，which is widely used in many fields including potential CO2 absorbent or phase-change agent，pharmaceuticals industry，fine chemical industry and petrochemical industry. The lately researches on the synthesis of per-O-acetyl glucopyranose are reviewed. In particular，the catalysts，including homogeneous catalysts，solid acid catalysts and enzyme catalysts，utilized in these acetylation reactions to improve the selective and yield of the product are described in detail. Among them，base catalysts (pyridine and sodium acetate)，acid catalysts (protonic acid and Lewis acid)，and solid acid catalysts (zeolite molecular sieve and heteropoly acid) have been received most attention. It shows that such reaction will be further studied to develop catalysts with higher catalytic activity，higher selectivity，low cost and easy handling.

Key words: per-O-acetyl glucopyranose, homogeneous catalysts, solid acid catalysts, enzyme catalysts

摘要： D-葡萄糖五乙酸酯是非常重要的糖类衍生物，在二氧化碳吸附、医药、精细化工和石油化工等领域用途广泛，关于D-葡萄糖五乙酸酯的合成、产物构型转化与控制是其热点研究方向。本文综述了D-葡萄糖五乙酸酯的催化合成研究进展，主要介绍了均相催化、固体酸催化、酶催化等方法合成D-葡萄糖五乙酸酯的研究情况，重点叙述了吡啶和乙酸钠等碱性催化剂、质子酸和路易斯酸等酸性催化剂、沸石分子筛和杂多酸等固体酸催化剂在D-葡萄糖五乙酸酯合成中的应用情况，指出开发催化活性高、选择性高、构型可调控的催化剂，并将其用于糖类化合物的酯化反应是未来重点研究的方向。

关键词: D-葡萄糖五乙酸酯, 均相催化, 固体酸催化, 酶催化