Abstract: This review summarizes the chemical and biological synthesis for xylonic acid production. By comparison，the microbial fermentation method is considered as one of the promising methods for xylonic acid production. Current status of microbial xylonic acid production is especially introduced，including strains，metabolite pathways and fermentation levels. In addition，the application prospects of xylonic acid is also discussed. It is proposed that future research should be emphasized on screening ideal microbe strains，analysis in the metabolic mechanism for xylose oxidation，and further investigation in xylonic acid application.

摘要： 综述了木糖酸的化学合成和生物合成方法，重点对微生物发酵的菌种、代谢途径和国内外发酵水平进行了总结，并对木糖酸的应用前景进行了展望。未来的研究重点应集中在木糖酸生物合成的代谢机理、高产木糖酸的菌种选育以及木糖酸的应用开发等方面。