Abstract: Ultrasonic and reflux assisted extraction of isoflavones from sorbean hull（ISH）was investigated. For the single-factor experiments，extraction temperature，concentration of ethanol and ultrasonic time were selected as the influencing factors. Combined with the response surface methodology，the extraction conditions for ISH was optimized as：temperature 83 ℃，ethanol concentration 84%，ultrasonic time 30 min，soybean hull size 150 μm，solvent to material 25:1，reflux extraction time 90 min and ultrasonic power 108 W. Under these optimized conditions，the extraction yield of ISH was up to 3.5 mg/g.

摘要： 利用超声萃取和回流萃取方法进行单因素实验，选取提取温度、超声时间和乙醇体积分数为影响因子，应用响应面法（RSM）优化大豆荚壳异黄酮的提取条件。结果表明，大豆荚壳异黄酮优化浸提条件为：提取温度83 ℃、乙醇体积分数为84%、超声时间30 min、大豆荚壳颗粒150 μm、液料比25:1、回流萃取时间90 min、超声功率108 W，大豆荚壳总异黄酮的得率为3.5 mg/g。响应面法大豆荚壳总异黄酮的提取条件优化合理可行，为提高大豆荚壳总异黄酮的提取率提供了依据。