Abstract: Molecular imprinted polymers (MIPs) were prepared by using luteolin as the template molecule，acrylamide as the functional monomer and EGDMA as the crosslinking agent. The prepared MIPs were used as solid-phase extraction (SPE) agent to extract luteolin from peanut hull，which exhibited very high selectivity and good recognition ability to luteolin. The obtained luteolin with the MIPs-SPE column has a purity of 96.2%，which is 20 percentage higher than that with silica gel column. Furthermore，compared with silica gel column，the MIPs-SPE column can be used for many times after elution and regeneration.

摘要： 采用分子印迹技术，以木犀草素为模板分子、丙烯酰胺为功能单体、EGDMA为交联剂，合成了木犀草素印迹聚合物。将该印迹聚合物用于固相萃取，分离提取花生壳中的木犀草素。结果表明，该印迹聚合物对木犀草素具有较高的吸附性能和选择性，用印迹柱萃取得到的木犀草素纯度高出硅胶柱分离近20个百分点，达到96.2%。且MIPs-SPE柱与普通的硅胶柱相比，经过洗脱再生后可以反复使用多次。