Abstract:

This review describes the recent research progress in microfluidic techniques applied in micro/nano-particle synthesis，including conventional microfluidic laminar flow and hydrodynamic focusing flow，microfluidic-formed disperse and continuous phases，and microdropletting，etc. The microfluidic techniques applied to synthesis of micro/nanoparticles appear developing trends from continuous flow to dispersed one. In addition，more sophisticated microfluidic devices specialized for particle synthesis are also described. Finally，some basic issues related to micromixing method for synthesis of micro/nanoparticles are discussed.

摘要：

综述了近三年来人们采用普通层流与聚焦层流、分散相与连续相形成技术、液滴技术等微流控技术角度来合成微纳米粒子的研究进展。这些进展反映出，微纳米粒子合成的微流控技术正在从连续微流动层流向离散态的分段流与液滴流技术的方向发展。文中对围绕基本微混合方式形成的特殊微流控结构被用于粒子合成的研究也给予了关注。最后对微流控微混合方式合成粒子技术过程中存在的一些基本问题作了讨论。