Abstract: Whole cell immobilization can improve the stability of biocatalysts，simplify the separation process of oil and biocatalysts from the aqueous medium，and then lower the production costs of the biocatalysts. Therefore，the immobilization technique is of great importance for accelerating the industrialization process of deep biodesulfurization of petroleum feedstocks. The development of whole cell immobilization methods and reactors for biodesulfurization of petroleum feedstocks are reviewed. Current problems existed and corresponding suggestions are discussed.

摘要： 发展固定化技术实现油品的生物深度脱硫，可以提高生物催化剂的稳定性，简化油水分离工艺和生物催化剂的回收工艺，降低生物催化剂的生产成本，对促进油品生物深度脱硫技术的产业化发展具有重要意义。本文综述了固定化细胞油品生物脱硫方法及固定化反应器研究进展，指出了目前存在的问题及可能的解决方案，并对油品生物脱硫技术今后的发展方向进行了展望。