Abstract: A type of antibacterial material were prepared and designed for surface contact disinfection by grafting polymeric quaternary ammonium salts onto cellulose fiber. Characterization of disinfection process using quaternary ammonium salts grafted cellulose fiber was carried out with S. aureus as model bacteria. A rapid adsorption of S. aureus on the grafted fiber was identified，as indicated by the dramatic reduction of the concentration of viable cells in the suspensions. The TTC-dehydrogenase activity and respiration activity of S. aureus adsorbed on the fiber surface were also determined. The adsorption of S. aureus on the fiber surface was observed with scanning electron microscopy (SEM)，which showed the lysis of cell envelope along with the processing. The results obtained in the present study showed that the disinfection process consisted of the adsorption of S. aureus on the fiber surface，activity restraining action and cell lysis.

摘要： 通过表面接枝的方法，在纤维素纤维表面引入具有抗菌功能的季铵盐聚合物，考察了抗菌纤维对金黄色葡萄球菌的抗菌过程特性。接枝抗菌材料可在短时间内迅速降低溶液中细菌的活菌量。采用TTC活性和菌体耗氧测定法与扫描电镜观察法研究了抗菌过程。结果表明，其抗菌过程由吸附、抑制活性和破裂杀灭3个步骤构成，被抗菌纤维吸附的金黄色葡萄球菌不具有繁殖能力。